SciELO - Scientific Electronic Library Online

vol.41 issue4Biochemical analysis of fetal fluids and cytology of the amniotic fluid of female Mocó (Kerodon rupestris)Parasitism by Acari and Phthiraptera on guinea pigs [Cavia porcellus (Linnaeus, 1758)] from rural and urban environment in Silva Jardim and Duque de Caxias municipal districts, Rio de Janeiro state, Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Brazilian Journal of Veterinary Research and Animal Science

Print version ISSN 1413-9596On-line version ISSN 1678-4456


SCHOSSLER, Deila Rosély C. et al. Syzygium cumini and the regeneration of insulin positive cells from the pancreatic duct. Braz. J. Vet. Res. Anim. Sci. [online]. 2004, vol.41, n.4, pp.236-239. ISSN 1413-9596.

Syzygium cumini is a plant that has been used in popular medicine for the treatment of insulin dependent diabetes mellitus (DMID). This study verified the effect of Syzygium cumini upon the regeneration of insulin producing cells in the pancreatic duct wall. The animals were divided into four groups, control (C), treated control (TC), diabetic control (DC) and treated diabetic (TD). An aqueous extract from Syzygium cumini bark was given by gavage in a daily dose of 1g/kg of body weight. After a thirty day period the animals were euthanized and the pancreas taken to immunohistochemical analysis. In this study, it was observed the positive staining for insulin on cells of the pancreatic duct and connective tissue in the pancreas of TD and TC animals. These results indicate that Syzygium cumini bark extract stimulates development of insulin positive cells from the pancreatic duct epithelial cells.

Keywords : Syzygium cumini; Alloxan; Diabetes; Immunohistochemistry.

        · abstract in Portuguese     · text in English     · English ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License