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MUZI, Camila Drumond; KOIFMAN, Sérgio  and  MONTEIRO, Gina Torres Rego. Occupation and brain tumors: a case-control study in the municipality of Rio de Janeiro, Brazil. Cad. saúde colet. [online]. 2012, vol.20, n.4, pp.506-514. ISSN 1414-462X.

This is a hospital-based case-control study with the objective of estimating the magnitude of association between the economic activity duration and occupation referred to the development of intracranial neoplasms in adults. We collected data on occupational history of 239 cases and 267 controls. Associations between economic activities and occupations and brain cancers were estimated by logistic regression. In the analysis of economic activities was found odds ratio with statistical significance between the number of brain tumors and Agriculture (OR: 2.52; 95%CI 1.15-5.53), and between meningiomas and transport area (OR: 3.14; 95%CI 1.08-9.19) and real estate (OR: 2.45; 95%CI 1.17-5.15), and risk estimate is not significant for meningiomas and Health and Social (OR: 3.55; 95%CI 0.89-14.16). The analysis by occupation presented risk estimates with statistical significance between brain tumors and farmers (OR: 2.44 95%CI 1.14-5.18) and between gliomas and office employees (OR: 2.33; 95%CI 1.02-5.29). The findings support the hypothesis of an association between economic activities/occupations and intracranial tumors, requiring more research to identify specific exposures.

Keywords : Neoplasms, Intracranial; occupations; case-control studies; occupational exposure.

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