Genetics and Molecular Biology
Print version ISSN 1415-4757
CARMO, Fausto Moreira da Silva et al. Association of MYF5 gene allelic variants with production traits in pigs. Genet. Mol. Biol. [online]. 2005, vol.28, n.3, pp. 363-369. ISSN 1415-4757. http://dx.doi.org/10.1590/S1415-47572005000300004.
We studied the phenotypic effects of polymorphisms at the MYF5 gene in a divergent F2 swine population and found that one polymorphism was due to an insertion and another to a deletion. The genotypes of 359 F2 animals were obtained and the Normal/Normal (NN) and Normal/Insertion (NI) genotypes analyzed to determine associations with phenotypic data for performance, carcass and meat quality traits. Significant differences were observed (p < 0.05) between NN and NI animals for drip (NN = 3.14 ± 1.56; NI = 3.69 ± 2.78%), cooking (NN = 32.26 ± 2.41; NI = 33.21 ± 2.31%) and total loss (NN = 34.16 ± 2.63 and NI = 34.97 ± 2.08%). The Deletion marker was not statistically tested. The results indicate that the allelic variant Insertion is associated with a deleterious effect on meat quality traits and should be monitored in marker assisted selection programs.
Keywords : myogenesis; DNA sequencing; pig production; PCR.