Genetics and Molecular Biology
versão impressa ISSN 1415-4757
ROCHA, Carlos Alberto Machado da et al. Studies of micronuclei and other nuclear abnormalities in red blood cells of Colossoma macropomum exposed to methylmercury. Genet. Mol. Biol. [online]. 2011, vol.34, n.4, pp.694-697. ISSN 1415-4757. http://dx.doi.org/10.1590/S1415-47572011000400024.
The frequencies of micronuclei (MN) and morphological nuclear abnormalities (NA) in erythrocytes in the peripheral blood of tambaqui (Colossoma macropomum), treated with 2 mg.L-1 methylmercury (MeHg), were analyzed. Two groups (nine specimens in each) were exposed to MeHg for different periods (group A - 24 h; group B - 120 h). A third group served as negative control (group C, untreated; n = 9). Although, when compared to the control group there were no significant differences in MN frequency in the treated groups, for NA, the differences between the frequencies of group B (treated for 120 h) and the control group were extremely significant (p < 0.02), thus demonstrating the potentially adverse effects of MeHg on C. macropomum erythrocytes after prolonged exposure.
Palavras-chave : cytotoxicity; genotoxicity; methylmercury; micronuclei assay.