Genetics and Molecular Biology
versão impressa ISSN 1415-4757
STARK, Alan e SENETA, Eugene. On S.N. Bernstein's derivation of Mendel's Law and 'rediscovery' of the Hardy-Weinberg distribution. Genet. Mol. Biol. [online]. 2012, vol.35, n.2, pp. 388-394. Epub 10-Maio-2012. ISSN 1415-4757. http://dx.doi.org/10.1590/S1415-47572012005000025.
Around 1923 the soon-to-be famous Soviet mathematician and probabilist Sergei N. Bernstein started to construct an axiomatic foundation of a theory of heredity. He began from the premise of stationarity (constancy of type proportions) from the first generation of offspring. This led him to derive the Mendelian coefficients of heredity. It appears that he had no direct influence on the subsequent development of population genetics. A basic assumption of Bernstein was that parents coupled randomly to produce offspring. This paper shows that a simple model of non-random mating, which nevertheless embodies a feature of the Hardy-Weinberg Law, can produce Mendelian coefficients of heredity while maintaining the population distribution. How W. Johannsen's monograph influenced Bernstein is discussed.
Palavras-chave : Bernstein; Mendel; Hardy-Weinberg; axiomatic foundations; coefficients of heredity.