PPARG rs1801282
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G = 0.09 |
Additive |
2.36 |
1.10–5.05 |
Caucasian |
González-Sánchez, et al., 2002González-Sánchez JL, Serrano Ríos M, Fernández Perez C, Laakso M and Martínez Larrad, MT (2002) Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol 147:495-501.
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G = 0.06 |
Dominant |
2.85 |
1.07–7.62 |
Caucasian |
Morini, et al., 2008Morini E, Tassi V, Capponi D, Ludovico O, Dallapiccola B, Trischitta V and Prudente S (2008) Interaction between PPARgamma2 variants and gender on the modulation of body weight. Obesity 16:1467-1470.
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G = 0.05 |
Dominant |
0.64 |
0.42–0.76 |
Chinese |
Wang, et al., 2013Wang X, Liu J, Ouyang Y, Fang M, Gao H and Liu L (2013) The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population. PLoS One 8:e71985.
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G = 0.11 |
Recessive |
3.2 |
1.2–12.9 |
Indian |
Bhatt, et al., 2012Bhatt S P, Misra A, Sharma M, Luthra K, Guleria R, Pandey RM and Vikram N K (2012) Ala/Ala genotype of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 gene is associated with obesity and insulin resistance in Asian Indians. Diabetes Technol Ther 14:828-834.
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G = 0.22
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Additive
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1.25
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0.73–2.15
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Mexican – Mestizo
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This study
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FTO rs9939609
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A = 0.19 |
Additive |
1.41 |
1.15–1.76 |
Mexican – Mestizo |
León-Mimila, et al., 2013León-Mimila P, Villamil-Ramírez H, Villalobos-Comparán M, Villarreal-Molina T, Romero-Hidalgo S, López-Contreras B, Gutiérrez-Vidal R, Vega-Badillo J, Jacobo-Albavera L, Posadas-Romeros C, et al. (2013) Contribution of common genetic variants to obesity and obesity-related traits in Mexican children and adults. PLoS One 8:e70640.
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A = 0.20 |
Additive |
2.42 |
1.71–3.44 |
Mexican – Mestizo |
Villalobos-Comparán, et al., 2008Villalobos-Comparán M, Teresa Flores-Dorantes M, Teresa Villarreal-Molina M, Rodríguez-Cruz M, García-Ulloa AC, Robles L, Huertas-Vázquez A, Saucedo-Villarreal N, López-Alarcón M, Sánchez-Muñoz F, et al. (2008) The FTO gene is associated with adulthood obesity in the Mexican population. Obesity 16:2296-2301.
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A = 0.12 |
Additive |
1.29 |
1.11–1.49 |
Chinese |
Xi, et al., 2010Xi B, Shen Y, Zhang M, Liu X, Zhao X, Wu L and Wang X (2010) The common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China. BMC Med Genet 11:e107.
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A = 0.42 |
Additive |
1.27 |
1.20–1.34 |
Caucasian |
Andreasen, et al., 2008 |
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A = 0.59 |
Recessive |
1.97 |
1.29–3.00 |
Caucasian |
Luczynski, et al., 2012Luczynski W, Zalewski G and Bossowski A (2012) The association of the FTO rs9939609 polymorphism with obesity and metabolic risk factors for cardiovascular diseases in Polish children. J Physiol Pharmacol 63:241-248.
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A = 0.35
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Additive
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1.27
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0.82–1.98
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Mexican – Mestizo
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This study
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ADIPOQ
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rs4632532 |
T = 0.48 |
Codominant |
Increase in BMI |
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Mexican – American |
Richardson, et al., 2005 |
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T = 0.45 |
Codominant |
Increase in BMI |
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Hispano – American |
Sutton, et al., 2005Sutton BS, Weinert S, Langefeld CD, Williams AH, Campbell JK, Saad MF and Bowden DW (2005) Genetic analysis of adiponectin and obesity in Hispanic families: The IRAS Family Study. Hum Genet 117:107-118.
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T = 0.61
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Additive
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1.47
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0.78–2.74
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Mexican – Mestizo
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This study
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rs182052 |
G = 0.37 |
Additive |
1.22 |
1.05–1.42 |
Afroamerican |
Bostrom, et al., 2008Bostrom MA, Freedman BI, Langefeld CD, Liu L, Hicks PJ and Bowden DW (2008) Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy. Diabetes 58:499-504.
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G = 0.48 |
Codominant |
Increase in BMI |
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Mexican – American |
Richardson, et al., 2005 |
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G = 0.44 |
Codominant |
Increase in BMI |
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Hispano – American |
Sutton, et al., 2005Sutton BS, Weinert S, Langefeld CD, Williams AH, Campbell JK, Saad MF and Bowden DW (2005) Genetic analysis of adiponectin and obesity in Hispanic families: The IRAS Family Study. Hum Genet 117:107-118.
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G = 0.63
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Additive
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1.43
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0.76–2.74
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Mexican – Mestizo
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This study
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