America |
Argentina |
69 |
0.15 |
0.49 |
Fundia et al., 2014Fundia AF, Weich N, Crivelli A, La Motta G, Larripa IB and Slavutsky I (2014) Glutathione S-transferase gene polymorphisms in celiac disease and their correlation with genomic instability phenotype. Clin Res Hepatol Gastroenterol 38:379-384.
|
|
Brazil |
137 |
0.26 |
0.38 |
Hatagima et al., 2004Hatagima A, Marques CF, Krieger H and Feitosa MF (2004) Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms in a Brazilian mixed population. Hum Biol 76:937-942.
|
|
Canada |
274 |
0.17 |
0.51 |
Krajinovic et al., 1999Krajinovic M, Labuda D, Richer C, Karimi S and Sinnett D (1999) Susceptibility to childhood acute lymphoblastic leukemia: Influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood 93:1496-1501.
|
|
Chile |
260 |
0.13 |
0.42 |
Acevedo et al., 2014Acevedo CA, Quiñones LA, Catalán J, Cáceres DD, Fullá JA and Roco AM (2014) Impact of CYP1A1, GSTM1, and GSTT1 polymorphisms in overall and specific prostate cancer survival. Urol Oncol 32:280-290.
|
|
Costa Rica |
2042 |
0.20 |
0.51 |
Cornelis et al., 2007Cornelis MC, El-Sohemy A and Campos H (2007) GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction. Am J Clin Nutr 86:752-758.
|
|
Mexico |
211 |
0.11 |
0.44 |
This study |
|
Paraguay |
67 |
0.18 |
0.36 |
Gaspar et al., 2002Gaspar PA, Hutz MH, Salzano FM, Hill K, Hurtado AM, Petzl-Erler ML, Tsuneto LT and Weimer TA (2002) Polymorphisms of CYP1a1, CYP2e1, GSTM1, GSTT1, and TP53 genes in Amerindians. Am J Phys Anthropol 119:249-256.
|
|
USA |
1752 |
0.21 |
0.52 |
Gates et al., 2008Gates MA, Tworoger SS, Terry KL, Titus-Ernstoff L, Rosner B, De Vivo I, Cramer DW and Hankinson SE (2008) Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 17:2436-2444.
|
|
Venezuela |
120 |
0.11 |
0.51 |
Chiurillo et al., 2013Chiurillo MA, Griman P, Santiago L, Torres K, Moran Y and Borjas L (2013) Distribution of GSTM1, GSTT1, GSTP1 and TP53 disease-associated gene variants in native and urban Venezuelan populations. Gene 531:106-111.
|
|
Greenland |
100 |
0.46 |
0.47 |
Buchard et al., 2007Buchard A, Sanchez JJ, Dalhoff K and Morling N (2007) Multiplex PCR detection of GSTM1, GSTT1, and GSTP1 gene variants: Simultaneously detecting GSTM1 and GSTT1 gene copy number and the allelic status of the GSTP1 Ile105Val genetic variant. J Mol Diagn 9:612-617.
|
Africa |
Cameroon |
126 |
0.47 |
0.28 |
Piacentini et al., 2011Piacentini S, Polimanti R, Porreca F, Martínez-Labarga C, De Stefano GF and Fuciarelli M (2011) GSTT1 and GSTM1 gene polymorphisms in European and African populations. Mol Biol Rep 38:1225-1230.
|
|
Egypt |
200 |
0.30 |
0.55 |
Hamdy et al., 2003Hamdy SI, Hiratsuka M, Narahara K, Endo N, El-Enany M, Moursi N, Ahmed MS and Mizugaki M (2003) Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population. Br J Clin Pharmacol 55:560-569.
|
|
Ethiopia |
153 |
0.37 |
0.44 |
Piacentini et al., 2011Piacentini S, Polimanti R, Porreca F, Martínez-Labarga C, De Stefano GF and Fuciarelli M (2011) GSTT1 and GSTM1 gene polymorphisms in European and African populations. Mol Biol Rep 38:1225-1230.
|
|
Gambia |
337 |
0.37 |
0.20 |
Wild et al., 2000Wild CP, Yin F, Turner PC, Chemin I, Chapot B, Mendy M, Whittle H, Kirk GD and Hall AJ (2000) Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia. Int J Cancer 86:1-7.
|
|
Ivory Coast |
133 |
0.33 |
0.36 |
Santovito et al., 2010Santovito A, Burgarello C, Cervella P and Delpero M (2010) Polymorphisms of cytochrome P450 1A1, glutathione s-transferases M1 and T1 genes in Ouangolodougou (Northern Ivory Coast). Genet Mol Biol 33:434-437.
|
|
Moroco |
60 |
0.22 |
0.45 |
Kassogue et al., 2014Kassogue Y, Quachouh M, Dehbi H, Quessar A, Benchekroun S and Nadifi S (2014) Effect of interaction of glutathione S-transferases (T1 and M1) on the hematologic and cytogenetic responses in chronic myeloid leukemia patients treated with imatinib. Med Oncol 31:47.
|
|
Nambia |
134 |
0.36 |
0.11 |
Fujihara et al., 2009Fujihara J, Yasuda T, Iida R, Takatsuka H, Fujii Y and Takeshita H (2009) Cytochrome P450 1A1, glutathione S-transferases M1 and T1 polymorphisms in Ovambos and Mongolians. Leg Med (Tokyo) Suppl 1:S408-S410.
|
|
Saudi Arabia |
513 |
0.25 |
0.55 |
Al-Dayel et al., 2008Al-Dayel F, Al-Rasheed M, Ibrahim M, Bu R, Bavi P, Abubaker J, Al-Jomah N, Mohamed GH, Moorji A, Uddin S, et al. (2008) Polymorphisms of drug-metabolizing enzymes CYP1A1, GSTT and GSTP contribute to the development of diffuse large B-cell lymphoma risk in the Saudi Arabian population. Leuk Lymphoma 49:122-129.
|
|
Somalia |
100 |
0.44 |
0.40 |
Buchard et al., 2007Buchard A, Sanchez JJ, Dalhoff K and Morling N (2007) Multiplex PCR detection of GSTM1, GSTT1, and GSTP1 gene variants: Simultaneously detecting GSTM1 and GSTT1 gene copy number and the allelic status of the GSTP1 Ile105Val genetic variant. J Mol Diagn 9:612-617.
|
|
South Africa |
96 |
0.20 |
0.23 |
Masimirembwa et al., 1998Masimirembwa CM, Dandara C, Sommers DK, Snyman JR and Hasler JA (1998) Genetic polymorphism of cytochrome P4501A1, microsomal epoxide hydrolase, and glutathione S-transferases M1 and T1 in Zimbabweans and Venda of southern Africa. Pharmacogenetics 8:83-85.
|
|
Tanzania |
220 |
0.25 |
0.33 |
Dandara et al., 2002Dandara C, Sayi J, Masimirembwa CM, Magimba A, Kaaya S, De Sommers K, Snyman JR and Hasler JA (2002) Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans. Clin Chem Lab Med 40:952-957.
|
|
Tunisia |
79 |
0.44 |
0.46 |
Ouerhani et al., 2006Ouerhani S, Tebourski F, Slama MR, Marrakchi R, Rabeh M, Hassine LB, Ayed M and Elgaaïed AB (2006) The role of glutathione transferases M1 and T1 in individual susceptibility to bladder cancer in a Tunisian population. Ann Hum Biol 33:529-535.
|
|
Zimbabwe |
150 |
0.26 |
0.24 |
Dandara et al., 2002Dandara C, Sayi J, Masimirembwa CM, Magimba A, Kaaya S, De Sommers K, Snyman JR and Hasler JA (2002) Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans. Clin Chem Lab Med 40:952-957.
|
Asia |
China |
763 |
0.39 |
0.52 |
Liu et al., 2009Liu L, Li C, Gao J, Li K, Gao L and Gao T (2009) Genetic polymorphisms of glutathione S-transferase and risk of vitiligo in the Chinese population. J Invest Dermatol 129:2646-2652.
|
|
India |
251 |
0.16 |
0.34 |
Dunna et al., 2013Dunna NR, Vure S, Sailaja K, Surekha D, Raghunadharao D, Rajappa S and Vishnupriya S (2013) Deletion of GSTM1 and T1 genes as a risk factor for development of acute leukemia. Asian Pac J Cancer Prev 14:2221-2224.
|
|
Iran |
280 |
0.23 |
0.49 |
Rafiee et al., 2010Rafiee L, Saadat I and Saadat M (2010) Glutathione S-transferase genetic polymorphisms (GSTM1, GSTT1 and GSTO2) in three Iranian populations. Mol Biol Rep 37:155-158.
|
|
Japan |
476 |
0.50 |
0.52 |
Hishida et al., 2005Hishida A, Terakura S, Emi N, Yamamoto K, Murata M, Nishio K, Sekido Y, Niwa T, Hamajima N and Naoe T (2005) GSTT1 and GSTM1 deletions, NQO1 C609T polymorphism and risk of chronic myelogenous leukemia in Japanese. Asian Pac J Cancer Prev 6:251-255.
|
|
Korea |
1700 |
0.51 |
0.54 |
Kim and Hong, 2012Kim JH and Hong YC (2012) GSTM1, GSTT1, and GSTP1 polymorphisms and associations between air pollutants and markers of insulin resistance in elderly Koreans. Environ Health Perspect 120:1378-1384.
|
|
Mongolia |
207 |
0.26 |
0.46 |
Fujihara et al., 2009Fujihara J, Yasuda T, Iida R, Takatsuka H, Fujii Y and Takeshita H (2009) Cytochrome P450 1A1, glutathione S-transferases M1 and T1 polymorphisms in Ovambos and Mongolians. Leg Med (Tokyo) Suppl 1:S408-S410.
|
|
Philippines |
127 |
0.25 |
0.59 |
Baclig et al., 2012Baclig MO, Alvarez MR, Lozada XM, Mapua CA, Lozano-Kühne JP, Dimamay MP, Natividad FF, Gopez-Cervantes J and Matias RR (2012) Association of glutathione S-transferase T1 and M1 genotypes with chronic liver diseases among Filipinos. Int J Mol Epidemiol Genet 3:153-159.
|
|
Singapore |
177 |
0.49 |
0.67 |
Chan et al., 2011Chan JY, Ugrasena DG, Lum DW, Lu Y and Yeoh AE (2011) Xenobiotic and folate pathway gene polymorphisms and risk of childhood acute lymphoblastic leukaemia in Javanese children. Hematol Oncol 29:116-123.
|
|
Syria |
172 |
0.17 |
0.23 |
Al-Achkar et al., 2014Al-Achkar W, Azeiz G, Moassass F and Wafa A (2014) Influence of CYP1A1, GST polymorphisms and susceptibility risk of chronic myeloid leukemia in Syrian population. Med Oncol 31:889.
|
|
Taiwan |
574 |
0.44 |
0.50 |
Fujihara et al., 2009Fujihara J, Yasuda T, Iida R, Takatsuka H, Fujii Y and Takeshita H (2009) Cytochrome P450 1A1, glutathione S-transferases M1 and T1 polymorphisms in Ovambos and Mongolians. Leg Med (Tokyo) Suppl 1:S408-S410.
|
|
Thailand |
81 |
0.48 |
0.58 |
Klinchid et al., 2009Klinchid J, Chewaskulyoung B, Saeteng S, Lertprasertsuke N, Kasinrerk W and Cressey R (2009) Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women. Cancer Genet Cytogenet 195:143-149.
|
|
Vietnam |
100 |
0.30 |
0.42 |
Agusa et al., 2010Agusa T, Iwata H, Fujihara J, Kunito T, Takeshita H, Minh TB, Trang PT, Viet PH and Tanabe S (2010) Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam. Toxicol Appl Pharmacol 242:352-362.
|
Europe |
Bulgaria |
112 |
0.16 |
0.52 |
Toncheva et al., 2004Toncheva DI, Von Ahsen N, Atanasova SY, Dimitrov TG, Armstrong VW and Oellerich M (2004) Identification of NQO1 and GSTs genotype frequencies in Bulgarian patients with Balkan endemic nephropathy. J Nephrol 17:384-389.
|
|
Croatia |
60 |
0.22 |
0.45 |
Zuntar et al., 2014Zuntar I, Petlevski R, Dodig S and Popovic-Grle S (2014) GSTP1, GSTM1 and GSTT1 genetic polymorphisms and total serum GST concentration in stable male COPD. Acta Pharm 64:117-29.
|
|
Czech Rep. |
67 |
0.22 |
0.57 |
Binková et al., 2002Binková B, Smerhovsky Z, Strejc P, Boubelík O, Stávková Z, Chvátalová I and Srám RJ (2002) DNA-adducts and atherosclerosis: A study of accidental and sudden death males in the Czech Republic. Mutat Res 501:115-128.
|
|
Denmark |
537 |
0.13 |
0.52 |
Buchard et al., 2007Buchard A, Sanchez JJ, Dalhoff K and Morling N (2007) Multiplex PCR detection of GSTM1, GSTT1, and GSTP1 gene variants: Simultaneously detecting GSTM1 and GSTT1 gene copy number and the allelic status of the GSTP1 Ile105Val genetic variant. J Mol Diagn 9:612-617.
|
|
Estonia |
202 |
0.18 |
0.55 |
Juronen et al., 2000Juronen E, Tasa G, Veromann S, Parts L, Tiidla A, Pulges R, Panov A, Soovere L, Koka K and Mikelsaar AV (2000) Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians. Exp Eye Res 71:447-452.
|
|
Finland |
482 |
0.13 |
0.47 |
Garte et al., 2001Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, et al. (2001) Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 10:1239-1248.
|
|
France |
115 |
0.26 |
0.49 |
Abbas et al., 2004Abbas A, Delvinquiere K, Lechevrel M, Lebailly P, Gauduchon P, Launoy G and Sichel F (2004) GSTM1, GSTT1, GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population: Different pattern of squamous cell carcinoma and adenocarcinoma. World J Gastroenterol 10:3389-3393.
|
|
Germany |
3054 |
0.17 |
0.52 |
Kabesch et al., 2004Kabesch M, Hoefler C, Carr D, Leupold W, Weiland SK and von Mutius E (2004) Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax 59:569-573.
|
|
Greece |
171 |
0.10 |
0.52 |
Dialyna et al., 2003Dialyna IA, Miyakis S, Georgatou N and Spandidos DA (2003) Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk. Oncol Rep 10:1829-1835.
|
|
Holland |
419 |
0.23 |
0.50 |
Garte et al., 2001Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, et al. (2001) Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 10:1239-1248.
|
|
Italy |
546 |
0.17 |
0.49 |
Palli et al., 2010Palli D, Polidoro S, D’Errico M, Saieva C, Guarrera S, Calcagnile AS, Sera F, Allione A, Gemma S, Zanna I, et al. (2010) Polymorphic DNA repair and metabolic genes: A multigenic study on gastric cancer. Mutagenesis 25:569-575.
|
|
Lithuania |
456 |
0.16 |
0.47 |
Danileviciute et al., 2012Danileviciute A, Grazuleviciene R, Paulauskas A, Nadisauskiene R and Nieuwenhuijsen MJ (2012) Low level maternal smoking and infant birthweight reduction: Genetic contributions of GSTT1 and GSTM1 polymorphisms. BMC Pregnancy Childbirth 12:161.
|
|
Poland |
365 |
0.21 |
0.45 |
Reszka et al., 2014Reszka E, Jablonowski Z, Wieczorek E, Jablonska E, Krol MB, Gromadzinska J, Grzegorczyk A, Sosnowski M and Wasowicz W (2014) Polymorphisms of NRF2 and NRF2 target genes in urinary bladder cancer patients. J Cancer Res Clin Oncol 140:1723-1731.
|
|
Russia |
352 |
0.19 |
0.50 |
Gra et al., 2010Gra O, Mityaeva O, Berdichevets I, Kozhekbaeva Z, Fesenko D, Kurbatova O, Goldenkova-Pavlova I and Nasedkina T (2010) Microarray-based detection of CYP1A1, CYP2C9, CYP2C19, CYP2D6, GSTT1, GSTM1, MTHFR, MTRR, NQO1, NAT2, HLA-DQA1, and AB0 allele frequencies in native Russians. Genet Test Mol Biomarkers 14:329-342.
|
|
Serbia |
50 |
0.40 |
0.56 |
Stosic et al., 2014Stosic I, Grujicic D, Arsenijevic S, Brkic M and Milosevic-Djordjevic O (2014) Glutathione S-transferase T1 and M1 polymorphisms and risk of uterine cervical lesions in women from central Serbia. Asian Pac J Cancer Prev 15:3201-3205.
|
|
Slovakia |
332 |
0.18 |
0.51 |
Garte et al., 2001Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, et al. (2001) Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 10:1239-1248.
|
|
Slovenia |
386 |
0.21 |
0.50 |
Petrovic and Peterlin, 2014Petrovic D and Peterlin B (2014) GSTM1-null and GSTT1-null genotypes are associated with essential arterial hypertension in patients with type 2 diabetes. Clin Biochem 47:574-577.
|
|
Spain |
461 |
0.20 |
0.42 |
Ruano-Ravina et al., 2014Ruano-Ravina A, Pereyra MF, Castro MT, Pérez-Ríos M, Abal-Arca J and Barros-Dios JM (2014) Genetic susceptibility, residential radon, and lung cancer in a radon prone area. J Thorac Oncol 9:1073-1080.
|
|
Sweden |
203 |
0.18 |
0.51 |
Bu et al., 2007Bu H, Rosdahl I, Holmdahl-Källen K, Sun XF and Zhang H (2007) Significance of glutathione S-transferases M1, T1 and P1 polymorphisms in Swedish melanoma patients. Oncol Rep 17:859-864.
|
|
Turkey |
140 |
0.21 |
0.55 |
Aydin-Sayitoglu et al., 2006Aydin-Sayitoglu M, Hatirnaz O, Erensoy N and Ozbek U (2006) Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias. Am J Hematol 81:162-170.
|
|
England |
1122 |
0.21 |
0.58 |
Garte et al., 2001Garte S, Gaspari L, Alexandrie AK, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Benhamou S, Boffetta P, et al. (2001) Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 10:1239-1248.
|
Oceania |
Australia |
1246 |
0.17 |
0.54 |
Spurdle et al., 2007Spurdle AB, Chang JH, Byrnes GB, Chen X, Dite GS, McCredie MR, Giles GG, Southey MC, Chenevix-Trench G and Hopper JL (2007) A systematic approach to analysing gene-gene interactions: Polymorphisms at the microsomal epoxide hydrolase EPHX and glutathione S-transferase GSTM1, GSTT1, and GSTP1 loci and breast cancer risk. Cancer Epidemiol Biomarkers Prev 16:769-774.
|