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Revista Brasileira de Plantas Medicinais

versão impressa ISSN 1516-0572

Resumo

OLIVEIRA, A.F. et al. Evaluation of the Brazilian ironwood (Caesalpinia ferrea Mart. ex Tul. var. ferrea) healing activity on cutaneous lesions of goats. Rev. bras. plantas med. [online]. 2010, vol.12, n.3, pp.302-310. ISSN 1516-0572.  http://dx.doi.org/10.1590/S1516-05722010000300007.

The aim of this study was to demonstrate the effects of the topical treatment with Brazilian ironwood (Caesalpinia ferrea) on cutaneous wounds. Fifteen male mongrel goats were divided into 3 groups according to the postoperative period ((7th, 14th and 21st days). The experimental wounds were treated with an ointment composed of Brazilian wood powder bark mixed with sterile vaseline, whereas controls were only treated with sterile Vaseline. The ointment and the sterile vaselin were daily applied on a standardized circular wound (16 cm2 area) in the thoracic region of each animal. Clinical, bacteriological, morphometric and histopathological evaluations were performed in the wounds at predetermined periods (7th, 14th and 21st postoperative days). Morphometrically, control wounds had smaller surgical areas and greater degree of contraction than those from the treated group. However, histologically, there was a complete epithelialization of the treated wounds on the 21st day, whereas control wounds required longer time for healing. In the microbiological evaluation performed at the moment of wound production, there was no bacterial growth. During biopsies, Enterobacteriaceae bacteria and Staphylococcus aureus were identified; from the 14th day, the latter was only observed in the control group. The topical use of Caesalpinia ferrea ointment was significantly efficient to help healing cutaneous wounds in goats.

Palavras-chave : wound; healing; goats; Caesalpinia ferrea.

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