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Revista Brasileira de Plantas Medicinais

Print version ISSN 1516-0572

Abstract

OLIVEIRA, A.C.B. et al. Pre-clinical toxicological evaluation of tea from the leaves of Morus nigra L. (Moraceae). Rev. bras. plantas med. [online]. 2013, vol.15, n.2, pp.244-249. ISSN 1516-0572.  http://dx.doi.org/10.1590/S1516-05722013000200012.

The aim of this study was to carry out a pre-clinical toxicological assay to analyze the toxicity of tea from the leaves of Morus nigra L. (Moraceae). The subchronic toxicity of this tea (CF-Mn) was orally evaluated during 30 days in rats. The control group was given water for comparison. During the experimental period, signs of toxicity, body weight variation, and water and food consumption were assessed. At the end of the experiment, the blood of animals was removed for analysis of hematological and biochemical parameters. No mortality and no toxicity signs were observed, indicating low toxicity of the plant. There was no alteration in the hematological and biochemical parameters. Under the study conditions, CF-Mn can be considered of low toxicity since it did not produce toxic effects in treated animals.

Keywords : Subchronic toxicity; Morus nigra L.; Moraceae.

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