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Revista Brasileira de Plantas Medicinais

versão impressa ISSN 1516-0572versão On-line ISSN 1983-084X

Resumo

SANTOS, R.F.E.P.; CONSERVA, L.M.; BASTOS, M.L.A.  e  CAMPESATTO, E.A.. Biological potential assessment of Tabebuia aurea (Silva Manso) as a source of bioactive molecules for antimicrobial, antiedematogenic and antiradical activity. Rev. bras. plantas med. [online]. 2015, vol.17, n.4, suppl.3, pp.1159-1168. ISSN 1516-0572.  http://dx.doi.org/10.1590/1983-084x/14_168.

The species of Bignoniaceae family and genus Tabebuia are widely used in the traditional medicine and have a great therapeutic potential. The aim of the current research was to evaluate the biological potential of the Tabebuia aurea, determining its antimicrobial activity by the microdilution broth method, to predict the anti-edematogenic Minimum Inhibitory Concentration (MIC) by ear edema assay induced by capsaicin; and the antiradical one, towards DPPH. The ethanol extracts of T. aureashowed no cytotoxicity, except for the flower ethanol extract in concentrations above > 0.5 mg mL-1. The ethanol extract of the flower was active, with bactericidal action, against S. epidermidis (MIC 0.06 mg ml-1) and the ethanol extract of moderately active recto S. epidermidis (CIM: 0.25 mg mL-1) and S. aureus (MIC: 0.50 mg mL-1) were bacteriostatic for both strains. Both extracts had antiedematogenic action on the inhibition of edema of 40.50% by the ethanol extract of the flower and 41.73% by leaf extract. T. aurea did not show antiradical activity. The results indicate the antibacterial and antiedematogenic profile with no cytotoxicity by the T. aurea. It suggests the continuation of tests with isolated fractions and substances of flowers and leaves of that plant species as well as in vivo trials, in order to enhance the evidences targeted on finding new herbal medicines.

Palavras-chave : Herbal Medicinal; Tabebuia aurea; Antimicrobials; Cell Viability.

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