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Revista Brasileira de Plantas Medicinais

versão impressa ISSN 1516-0572versão On-line ISSN 1983-084X

Resumo

CORDOVIL, K. et al. Review of Medicinal Cajanus cajan of properties in Sickle Cell Disease. Rev. bras. plantas med. [online]. 2015, vol.17, n.4, suppl.3, pp.1199-1207. ISSN 1516-0572.  http://dx.doi.org/10.1590/1983-084x/14_139.

This article describes the occurrence, botanical characteristics, phytochemical and nutritional composition of pigeonpea [Cajanus cajan (L.) Millsp], and their relationship in the process inhibition of sickling in sickle cell disease (SCD), a genetic disorder that affects red blood cells, causing hemolysis and chronic anemia. Two chemical components would be related to the inhibitory effect on sickling of sickle cells: the L-phenylalanine and the p- hydroxybenzoic acid. In Brazil, detailed studies with pigeonpea chemical-biological may clarify the mechanisms by which the inhibition of sickling of red blood cells occurs, reducing oxidative stress and thus helping treating people affected by this disease.

Palavras-chave : medicinal properties; cajanus cajan; sickle cell anemia.

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