Abstract

GUARIENTO, Maria Elena; OLGA, Elza; MUSCELLI, Ana  and  GONTIJO, José Antonio Rocha. Chronotopic and blood pressure response to oral glucose load in chagas' disease. Sao Paulo Med. J. [online]. 1994, vol.112, n.3, pp. 602-606. ISSN 1516-3180.  http://dx.doi.org/10.1590/S1516-31801994000300006.

Cardiac chronotropic and pressor responses after an oral load of glucose were assessed in sixteen Chagasic subjects and 28 controls by means of blood pressure and pulse rate measurements. Cardiovascular response was correlated with serum insulin and glucose levels. The experiment identified a subgroup of Chagasic subjects (n=8) with a hypoinsulinemic behavior presenting less chronotropic and pressor responses than controls. This may indicate a lower insulin activity and/or an early Autonomic Nervous System dysfunction in this subgroup.

Keywords : Cardiovascular response; insulinemic response; Autonomic Nervous System; South America Trypanosomiasis.