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Sao Paulo Medical Journal

Print version ISSN 1516-3180

Abstract

COUTO, Egle et al. Anticardiolipin antibody in recurrent spontaneous aborting and fertile women. Sao Paulo Med. J. [online]. 1998, vol.116, n.4, pp. 1760-1765. ISSN 1516-3180.  http://dx.doi.org/10.1590/S1516-31801998000400004.

OBJECTIVE: To determine the association between the presence of anticardiolipin antibody and a history of recurrent spontaneous abortion. STUDY DESIGN: clinical controlled study LOCATION: Department of Gynecology and Obstetrics - University of Campinas (UNICAMP) SUBJECTS: 52 individuals with recurrent spontaneous abortion were included in Group 1 and 104 individuals with at least one live born child in Group 2. Elapsed time from last delivery to blood sampling varied from six months to two years. METHOD: Between November 1993 and November 1994, patients' blood samples were screened for anticardiolipin antibody by ELISA, as described by Triplett, Barna and Unger (1993). ANALYSIS: Chi-square and Fisher's Exact tests were used for statistical analysis. Student's "t" test was used to compare the means. RESULTS: There was no statistical difference in the presence of the anticardiolipin antibody between Group I (zero and 2.9%) and Group 2 (7.7 and 5.8%). CONCLUSION: There was no association between the presence of anticardiolipin antibody and recurrent spontaneous abortion.

Keywords : Anticardiolipin antibody; Recurrent spontaneous abortion; Immunology; Antiphospholipid syndrome.

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