Sao Paulo Medical Journal
On-line version ISSN 1806-9460
SAAD, Ivete Alonso Bredda; BOTEGA, Neury José and TORO, Ivan Felizardo Contrera. Predictors of quality-of-life improvement following pulmonary resection due to lung cancer. Sao Paulo Med. J. [online]. 2007, vol.125, n.1, pp. 46-49. ISSN 1806-9460. http://dx.doi.org/10.1590/S1516-31802007000100009.
CONTEXT AND OBJECTIVE: There is increasing involvement of health professionals in organizing protocols to determine the impact of lung surgery on functional state and activities of daily living, with the aim of improving quality of life (QoL). The objective of this study was to investigate predictors of QoL improvement among patients undergoing parenchyma resection due to lung cancer. DESIGN AND SETTING: Prospective study, at teaching hospital of Universidade Estadual de Campinas (Unicamp). METHODS: 36 patients with lung cancer diagnosis were assessed before surgery and on the 30th, 90th and 180th days after surgery. The Short-Form Health Survey (SF-36) was used as the dependent variable. The independent variables were the Hospital Anxiety and Depression (HAD) scale, a six-minute walking test (6-MWT), a visual analogue scale for pain, forced vital capacity (FVC), type of surgery and use of radiotherapy and chemotherapy. Generalized estimation equations (GEE) were utilized. RESULTS: The median age for these 20 men and 16 women was 55.5 ± 13.4 years. Both FVC and 6-MWT were predictors of improvement in the physical dimensions of QoL (p = 0.011 and 0.0003, respectively), as was smaller extent of surgical resection (p = 0.04). The social component of QoL had improved by the third postoperative month (p = 0.0005). CONCLUSION: The predictors that affected QoL positively were better FVC and 6-MWT results and less extensive lung resection. Three months after the surgery, an improvement in social life was already seen.
Keywords : Quality of life; Neoplasms; Medical oncology; Rehabilitation; Questionnaires.