SciELO - Scientific Electronic Library Online

 
vol.130 issue4Mentors also need support: a study on their difficulties and resources in medical schoolsLeukocyte adhesion deficiency syndrome: report on the first case in Chile and South America author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Sao Paulo Medical Journal

Print version ISSN 1516-3180

Abstract

CABRERIZO-GARCIA, José Luis; SEBASTIAN-ROYO, Mariano; MONTES, Nerea  and  ZALBA-ETAYO, Begoña. Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency. Sao Paulo Med. J. [online]. 2012, vol.130, n.4, pp. 259-262. ISSN 1516-3180.  http://dx.doi.org/10.1590/S1516-31802012000400010.

CONTEXT: Decreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits. CASE REPORT: We present the case of a patient with subacute combined spinal cord degeneration and pancytopenia secondary to severe and sustained vitamin B12 deficiency. Such cases are rare nowadays and have potentially fatal consequences. CONCLUSIONS: Vitamin B12 deficiency should be taken into consideration in the differential diagnosis in cases of blood disorders or severe neurological symptoms. Early diagnosis and treatment can avoid irreversible consequences.

Keywords : Vitamin B 12 deficiency; Subacute combined degeneration; Pancytopenia; Digestive system abnormalities; Nervous system diseases.

        · abstract in Spanish     · text in English     · pdf in English