Honey (apitherapy)33. Jull AB, Cullum N, Dumville JC, et al. Honey as a topical treatment for wounds. Cochrane Database Syst Rev. 2015;(3):CD005083. PMID: 25742878; doi: 10.1002/14651858.CD005083.pub4. https://doi.org/10.1002/14651858.CD00508...
|
People with acute and/or chronic wounds |
Conventional dressings for treatment of burns |
• Honey dressings heal partial thickness burns more quickly than conventional dressings |
High |
• No difference in overall risk of healing within six weeks for honey, compared with silver sulfadiazine |
High |
• Burns treated with honey heal more quickly than those treated with silver sulfadiazine |
Very low |
• Burns treated with honey presented lower risk of adverse events than the silver sulfadiazine group |
High |
Honey (apitherapy)44. Oduwole O, Udoh EE, Oyo-Ita A, Meremikwu MM. Honey for acute cough in children. Cochrane Database Syst Rev. 2018;4:CD007094. PMID: 29633783; doi: 10.1002/14651858.CD007094.pub5. https://doi.org/10.1002/14651858.CD00709...
|
Acute cough in children |
Dextromethorphan, diphenhydramine, no treatment and placebo |
• Use of honey was associated with reduced frequency of coughing, compared with the no treatment group |
Moderate |
• Use of honey was associated with reduced frequency of coughing, compared with placebo |
High |
• There was no difference between use of honey and use of dextromethorphan |
Moderate |
• Use of honey was associated with reduced frequency of coughing, compared with diphenhydramine |
Low quality |
Venom immunotherapy (apitherapy)55. Boyle RJ, Elremeli M, Hockenhull J, et al. Venom immunotherapy for preventing allergic reactions to insect stings. Cochrane Database Syst Rev. 2012;10:CD008838. PMID: 23076950; doi: 10.1002/14651858.CD008838.pub2. https://doi.org/10.1002/14651858.CD00883...
|
Preventing allergic reactions to insect stings |
No intervention |
• Use of venom immunotherapy versus no intervention reduced the risk of any systematic reaction to an insect sting |
High |
• Reduction in the risk of large local reaction favoring venom immunotherapy |
Moderate |
• The relative risk of any systematic reaction to treatment was higher with venom immunotherapy |
Moderate |
Aromatherapy77. Hines S, Steels E, Chang A, Gibbons K. Aromatherapy for treatment of postoperative nausea and vomiting. Cochrane Database Syst Rev. 2018;3:CD007598. PMID: 29523018; doi: 10.1002/14651858.CD007598.pub3. https://doi.org/10.1002/14651858.CD00759...
|
Postoperative nausea and vomiting |
Placebo, peppermint aromatherapy and isopropyl alcohol aromatherapy |
• Aromatherapy reduced the use of rescue antiemetic medication, compared with placebo |
Low |
• No difference between aromatherapy and placebo regarding: |
|
a) Severity of nausea |
Low |
b) Duration of nausea |
Very low |
• No difference between peppermint aromatherapy and placebo regarding severity of nausea at five minutes |
Low |
• Isopropyl alcohol aromatherapy showed benefits in relation to placebo for the following outcomes: |
|
a) time (in minutes) to 50% reduction of nausea score |
Moderate |
b) proportion of patients requiring antiemetics |
Moderate |
Aromatherapy88. Forrester LT, Maayan N, Orrell M, et al. Aromatherapy for dementia. Cochrane Database Syst Rev. 2014. ;(2):CD003150. PMID: 24569873; doi: 10.1002/14651858.CD003150.pub2. https://doi.org/10.1002/14651858.CD00315...
|
Dementia |
Placebo aromatherapy |
This review included two RCTs with divergent results. No meta-analysis was performed because of heterogeneity and lack of data |
Not assessed |
Aromatherapy1010. Smith CA, Collins CT, Crowther CA. Aromatherapy for pain management in labour. Cochrane Database Syst Rev. 2011;(7):CD009215. PMID: 21735438; doi: 10.1002/14651858.CD009215. https://doi.org/10.1002/14651858.CD00921...
|
Pain management in labor |
Standard care |
No difference between groups regarding: |
Not assessed |
a) assisted vaginal delivery risk |
|
b) cesarean section risk |
|
c) risk of neonatal intensive care admission |
|
Hypnosis (hypnotherapy)1313. Nishi D, Shirakawa MN, Ota E, Hanada N, Mori R. Hypnosis for induction of labour. Cochrane Database Syst Rev. 2014;(8):CD010852. PMID: 25118632; doi: 10.1002/14651858.CD010852.pub2. https://doi.org/10.1002/14651858.CD01085...
|
Pain management during labor and childbirth |
Placebo, no treatment or any analgesic drug or technique |
• Use of pharmacological pain relief or anesthesia was lower in the group that received self-hypnosis or hypnotherapy, compared with standard care |
Very low |
• No difference was found between the groups regarding: |
|
a) satisfaction with pain relief |
Low |
b) spontaneous vaginal birth |
Low |
Hypnosis (hypnotherapy)1515. Izquierdo de Santiago A, Khan M. Hypnosis for schizophrenia. Cochrane Database Syst Rev. 2007;(4):CD004160. PMID: 17943812; doi: 10.1002/14651858.CD004160.pub3. https://doi.org/10.1002/14651858.CD00416...
|
Schizophrenia |
Any treatment or standard therapy |
• No difference was found between hypnosis and standard care in relation to the brief psychiatric rating scale |
Not assessed |
Hypnosis (hypnotherapy)1616. Barnes J, Dong CY, McRobbie H, Walker N, Mehta M, Stead LF. Hypnotherapy for smoking cessation. Cochrane Database Syst Rev. 2010;(10):CD001008. PMID: 2092772; doi: 10.1002/14651858.CD001008.pub2. https://doi.org/10.1002/14651858.CD00100...
|
Smoking cessation |
No intervention and other intervention strategies |
• Benefit in hypnotherapy group regarding the probability of smoking cessation at 12 months, compared with no treatment |
Not assessed |
• Compared with psychological treatments, hypnotherapy alone did not improve smoking cessation at six months |
|
Ozone therapy1717. Liu J, Zhang P, Tian J, Li L, Li J, Tian JH, Yang K. Ozone therapy for treating foot ulcers in people with diabetes. Cochrane Database Syst Rev. 2015;(10):CD008474. PMID: 26505864; doi: 10.1002/14651858.CD008474.pub2. https://doi.org/10.1002/14651858.CD00847...
|
Foot ulcers in people with diabetes |
Antibiotic treatment or standard care |
Compared with standard care, the ozone therapy group showed no difference regarding: |
Not assessed |
• Ulcer area |
|
• Number of ulcers healed |
|
• Amputation rate |
|
• Adverse events |
|