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Sao Paulo Medical Journal

Print version ISSN 1516-3180On-line version ISSN 1806-9460


APODACA-RUEDA, Márcio et al. Solitary pancreatic metastasis from breast cancer: case report and review of literature. Sao Paulo Med. J. [online]. 2019, vol.137, n.2, pp.201-205.  Epub Nov 06, 2017. ISSN 1806-9460.



Pancreatic metastases from primary malignant tumors at other sites are rare, constituting about 2% of the neoplasms that affect the pancreas. Pancreatic metastasis from breast cancer is extremely rare and difficult to diagnose, because its clinical and radiological presentation is similar to that of a primary pancreatic tumor.


A 64-year-old female developed a lesion in the pancreatic tail 24 months after neoadjuvant therapy, surgery and adjuvant radiation therapy for right-side breast cancer (ductal carcinoma). She underwent distal pancreatectomy with splenectomy and left adrenalectomy, and presented an uneventful outcome. The immunohistochemical analysis on the surgical specimen suggested that the lesion originated from the breast.


In cases of pancreatic lesions detected in patients with a previous history of breast neoplasm, the possibility of pancreatic metastasis should be carefully considered.

Keywords : Breast neoplasms; Pancreas; Neoplasm metastasis; Pancreatic neoplasms; Carcinoma, ductal, breast.

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