SciELO - Scientific Electronic Library Online

vol.23 suppl.2Transtorno obsessivo-compulsivo resistente: conceito e estratégias de tratamentoTerapia comportamental do transtorno obsessivo-compulsivo author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Brazilian Journal of Psychiatry

Print version ISSN 1516-4446On-line version ISSN 1809-452X


CORDIOLI, Aristides V. Principais efeitos colaterais das drogas antiobsessivas e seu manejo. Rev. Bras. Psiquiatr. [online]. 2001, vol.23, suppl.2, pp.58-61. ISSN 1516-4446.

Selective serotonin reuptake inhibitors (SSRIs), clomipramine, and behavior therapy are the first line treatments for obsessive-compulsive (OCD) symptoms. One of the main reasons for treatment non-compliance and early discontinuation of medications by patients or premature change in prescriptions by clinicians are their side effects. Nausea, headache, insomnia, restlessness, sexual dysfunction, and tremors are common with SSRIs; hypotension, dry mouth, constipation, urinary retention, blurred vision, weight gain, sedation and cardiocirculatory problems, with clomipramine. The strategies and guidelines for these drugs' side effects management are here reviewed, based mainly in case reports and clinical experience. The clinician should be aware of the importance of addressing this issue, educating patients about the most frequent adverse reactions, and how to deal with them in order to prevent unwanted medication discontinuation, and enhance compliance with the treatment.

Keywords : Obsessive-compulsive disorder; Treatment; Selective serotonin reuptake inhibitors; Clomipramine; Adverse effects; Management.

        · text in Portuguese     · Portuguese ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License