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Brazilian Journal of Psychiatry

versão impressa ISSN 1516-4446versão On-line ISSN 1809-452X


MOREIRA, Fernanda P. et al. Gender differences of cannabis smoking on serum leptin levels: population-based study. Rev. Bras. Psiquiatr. [online]. 2018, vol.40, n.2, pp.216-219.  Epub 01-Fev-2018. ISSN 1516-4446.


To evaluate the serum leptin levels in cannabis smokers.


This was a cross-sectional population-based study of participants between the ages of 18 and 35 years. The data were collected through a self-administered questionnaire covering sociodemographic data and the use of psychoactive substances. Leptin levels were measured using a commercial ELISA kit.


Of the 911 participants, 6.7% were identified as cannabis smokers and had significantly lower leptin levels (p = 0.008). When stratified by gender, there was a significant decrease in leptin levels among male smokers (p = 0.039).


Cannabis smoking was linked to leptin levels in men, suggesting that the response to biological signals may be different between men and women.

Palavras-chave : Cannabis sativa; leptin; young adults; gender.

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