Carmi112112. Carmi L, Alyagon U, Barnea-Ygael N, Zohar J, Dar R, Zangen A. Clinical and electrophysiological outcomes of deep TMS over the medial prefrontal and anterior cingulate cortices in OCD patients. Brain Stimul. 2018;11:158-65.
|
41 OCD patients, 38 completers, 38 reported. |
H7 coil, 20 Hz (50,000 total pulses), or 1 Hz (22,500 total pulses), 100-110% RMT.4 cm anterior to the hot spot. |
20 Hz significantly better than sham at completion and 1 week follow up. |
Un-blinding and removal of 1 Hz group prior to study completion. |
Ceccanti113113. Ceccanti M, Inghilleri M, Attilia ML, Raccah R, Fiore M, Zangen A, et al. Deep TMS on alcoholics: effects on cortisolemia and dopamine pathway modulation. A pilot study. Can J Physiol Pharmacol. 2015;93:283-90.
|
18 male patients with alcohol use disorder, three completers, 18 reported. |
H-coil, 20 Hz (15,000 total pulses), 120% RMT.5 cm anterior to the hot spot. |
Reduced alcohol intake up to 3 months in active group after completion. |
No intergroup difference in clinical outcomes, but significant reduction of prolactinemia and cortisolemia. |
Enticott114114. Enticott PG, Fitzgibbon BM, Kennedy HA, Arnold SL, Elliot D, Peachey A, et al. A double-blind, randomized trial of deep repetitive transcranial magnetic stimulation (rTMS) for autism spectrum disorder. Brain Stimul. 2014;7:206-11.
|
30 high-functioning autistic adults, 19 completers, 18 reported. |
H-coil, 5 Hz (15,000 total pulses), 100% RMT.7 cm anterior to the hot spot. |
Social relations improved in active group. |
Significant differences only in subscales, full clinical measures scores unaffected. |
Herrmann115115. Herrmann MJ, Katzorke A, Busch Y, Gromer D, Polak T, Pauli P, et al. Medial prefrontal cortex stimulation accelerates therapy response of exposure therapy in acrophobia. Brain Stimul. 2017;10:291-7.
|
47 acrophobic patients, 44 completers, 39 reported. |
Round coil, 10 Hz (3,120 total pulses), 100% RMT. Reference point 10% of nasion-inion distance. |
Acrophobic symptoms improved in active group. |
Results were not sustained at 3 months follow up. |
Isserles116116. Isserles M, Shalev AY, Roth Y, Peri T, Kutz I, Zlotnick E, et al. Effectiveness of deep transcranial magnetic stimulation combined with a brief exposure procedure in post-traumatic stress disorder-a pilot study. Brain Stimul. 2013;6:377-83.
|
30 PTSD patients, 25 completers, 26 reported. |
H-coil, 20 Hz (20,160 total pulses), 120% RMT.3 cm above nasion. |
Improvement in rTMS + traumatic exposure group for up to 2 months follow up. |
No intergroup difference with control or rTMS + no exposure groups. Exposure procedure not measured for effectiveness. |
Kreuzer117117. Kreuzer PM, Schecklmann M, Lehner A, Wetter TC, Poeppl TB, Rupprecht R, et al. The ACDC pilot trial: targeting the anterior cingulate by double cone coil rTMS for the treatment of depression. Brain Stimul. 2015;8:240-6.
|
45 patients with moderate/severe depression, 40 completers, 40 reported. |
Double cone (mPFC) or figure-of-eight (dlPFC), 10 Hz (30,000 total pulses), 110% RMT.1.5 cm anterior to one-third of nasion-inion distance (mPFC stimulation site). |
mPFC group responded better than dlPFC group by the end of treatment sessions. |
Significant difference in mPFC vs. dlPFC group. Neither group differed from sham. |