SciELO - Scientific Electronic Library Online

 
vol.17 número3The Expression of Can and Camk is Associated with Lipogenesis in the Muscle of ChickenWELFARE OF BROILERS INGESTING A PRE-SLAUGHTER HYDRIC DIET OF LEMON GRASS índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Brazilian Journal of Poultry Science

versão impressa ISSN 1516-635Xversão On-line ISSN 1806-9061

Resumo

HAN, C et al. CHANGE OF THE MTOR PATHWAY IN TISSUES OF OVERFED GEESE. Rev. Bras. Cienc. Avic. [online]. 2015, vol.17, n.3, pp.293-300. ISSN 1516-635X.  https://doi.org/10.1590/1516-635x1703293-300.

This study aimed at examining the effect of overfeeding on the activity of the mTOR pathway in the liver and muscle tissues of Gang geese. Eighty healthy male Gang geese were reared under the same feeding conditions, and were divided at 14 weeks of age into a control group and an overfed group. All birds were slaughtered after three weeks of over feeding. Gene expression and protein content of several genes involved in the mTOR pathway were evaluated. The results showed that the gene expression of mTOR, raptor, and rictor, and the protein contents of mTOR and PI3K were higher in liver, breast muscle, and leg muscle of the overfed group than that of control group. However, the S6K expression level was clearly lower in the liver of the overfed group than that of control group, and there was no evident difference in both breast muscle and leg muscle between the control group and the overfed group. These results suggest that overfeeding induces the activity of raptor, rictor, and mTOR, and that mTOR signaling pathway was closely linked with PI3K pathway in the evaluated geese.

Palavras-chave : Goose; mTOR pathway; overfeeding; tissues.

        · texto em Inglês     · Inglês ( pdf )