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Hematopoietic stem cell transplantation for autoimmune diseases in Brazil: current status and future prospectives

O transplante de células precursoras hematopoéticas em doenças autoimunes no Brasil: estado atual e perspectivas

In this paper, we discuss the launching of a cooperative protocol of hematopoietic stem cell transplantation for autoimmune diseases in Brazil. We present specific conditions of the country's health system which would affect the trial, preliminary results of the first nine patients transplanted under the protocol (4 systemic lupus, 3 multiple sclerosis, one systemic sclerosis and one overlapping lupus + systemic sclerosis) and future prospectives of organizing phase III randomized trials to answer specific scientific questions pending in the field.

Hematopoietic stem cell transplantation; autoimmune diseases; autologous transplantation; systemic lupus erythematosus; multiple sclerosis; systemic sclerosis


Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular R. Dr. Diogo de Faria, 775 cj 114, 04037-002 São Paulo/SP/Brasil, Tel. (55 11) 2369-7767/2338-6764 - São Paulo - SP - Brazil
E-mail: secretaria@rbhh.org