SciELO - Scientific Electronic Library Online

vol.26 issue4Challenges in current chronic myeloid leukemia therapy of imatinib era author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Hematologia e Hemoterapia

Print version ISSN 1516-8484On-line version ISSN 1806-0870


SILVA, Célia R. G.; JORGE, Antonio O. C.  and  HIRTSCH, Iracema M. V.. Anti-Diego (a) alloantibody in pregnant. Rev. Bras. Hematol. Hemoter. [online]. 2004, vol.26, n.4, pp.285-287. ISSN 1516-8484.

The Diego blood group system is composed of two principal antigens Diegoa (Dia) and Diegob (Dib). In the Caucasian population the prevalence of Dia is rare with a frequency of about 0.02% and can lead to the production of antibodies that are important in newborn babies and in transfusional medicine. The present study reports on anti-Dia antibodies in a Caucasian pregnant woman, detected by indirect anti-globulin testing shortly before delivery. The direct anti-globulin test of the newborn's blood cord was negative because its phenotype was Di (a- b+). So the newborn did not develop any hemolytic diseases. A phenotyping study of the whole family was performed which revealed that probably the mother became sensitive during her second pregnancy of twins where the two children presented with the Dia antigen phenotype inherited from the father.

Keywords : Alloimunization; anti-Di (a); Diego blood groups system.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License