Resumo

SILVA, Célia R. G.; JORGE, Antonio O. C.  e  HIRTSCH, Iracema M. V.. Anti-Diego (a) alloantibody in pregnant. Rev. Bras. Hematol. Hemoter. [online]. 2004, vol.26, n.4, pp. 285-287. ISSN 1516-8484.  http://dx.doi.org/10.1590/S1516-84842004000400010.

The Diego blood group system is composed of two principal antigens Diego^a (Di^a) and Diego^b (Di^b). In the Caucasian population the prevalence of Di^a is rare with a frequency of about 0.02% and can lead to the production of antibodies that are important in newborn babies and in transfusional medicine. The present study reports on anti-Di^a antibodies in a Caucasian pregnant woman, detected by indirect anti-globulin testing shortly before delivery. The direct anti-globulin test of the newborn's blood cord was negative because its phenotype was Di (a- b+). So the newborn did not develop any hemolytic diseases. A phenotyping study of the whole family was performed which revealed that probably the mother became sensitive during her second pregnancy of twins where the two children presented with the Di^a antigen phenotype inherited from the father.

Palavras-chave : Alloimunization; anti-Di (a); Diego blood groups system.