Revista Brasileira de Hematologia e Hemoterapia
versión impresa ISSN 1516-8484
versión On-line ISSN 1806-0870
BALAU, Ana Julia; DE NADAI, Livia C.; BRESSAN, Mônica S. y SIMAO, Josiane L.. Treatment of giant hemangioma with interferon-alpha: report of two cases. Rev. Bras. Hematol. Hemoter. [online]. 2007, vol.29, n.4, pp.406-411. ISSN 1516-8484. http://dx.doi.org/10.1590/S1516-84842007000400015.
The aim of this study is to describe the treatment using interferon-alpha of giant hemangiomas in children. The authors report two cases of children presenting with giant hemangiomas treated using interferon-alpha and analyze the results. IBS, 3 years-old, has been followed up in Famema Hemathology Service since she was 1 year-old with a tumor on the face and persistent bleeding. After clinical and radiologic evaluations and suggested the diagnosis of giant hemangioma, she started treatment with interferon-alpha. A great clinical improvement was observed a reducing of the number of episodes of bleedings and a decrease in of the tumor size. CNP, 12 years-old, came to this service in the last year presenting with a small painful tumor on the left knee. She had already tried a treatment with Prednisone with no improvement. Treatment with interferon-alpha was initiated with a significant decrease in its size. The use of interferon-alpha should be considered in the treatment of giant hemangioma due to its favorable results related to a reduction in the tumor size and the episodes of bleeding.
Palabras clave : Hemangioma; alpha-interferon; bleeding; child.