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Revista Brasileira de Hematologia e Hemoterapia

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Abstract

CASTRO, Alana Jocelina Montenegro de; GONCALVES, Romelia Pinheiro  and  PITOMBEIRA, Maria Helena da Silva. Bone marrow cytomorphological changes in patients co-infected with visceral leishmaniasis and human immunodeficiency virus. Rev. Bras. Hematol. Hemoter. [online]. 2011, vol.33, n.6, pp. 484-484. ISSN 1516-8484.  http://dx.doi.org/10.5581/1516-8484.20110129.

Visceral leishmaniasis (VL) is a severe systemic infectious disease.(1) It has been recognized as an opportunistic disease in patients infected with human immunodeficiency virus (HIV).(2,3) The analysis of the bone marrow of patients co-infected with VL and HIV showed dysplasia of erythroid, granulocytic and megakaryocytic lineages (Figure 1), besides the presence of plasmacytosis, cytoplasmic bodies, hemophagocytosis, granuloma and intracellular and extracellular leishmania amastigotes (Figure 2). These findings are found in the analysis of bone marrow of patients co-infected with HIV and VL; knowledge of these findings may be useful for the diagnosis and prognosis of patients.

Keywords : HIV infections; Bone marrow examination; Leishmaniasis, visceral; AIDS-related opportunistic infections.

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