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Revista Brasileira de Hematologia e Hemoterapia

Print version ISSN 1516-8484

Abstract

NUCCI, Marcio. Use of antifungal drugs in hematology. Rev. Bras. Hematol. Hemoter. [online]. 2012, vol.34, n.5, pp. 383-391. ISSN 1516-8484.  http://dx.doi.org/10.5581/1516-8484.20120095.

Invasive fungal disease represents a major complication in hematological patients. Antifungal agents are frequently used in hematologic patients for different purposes. In neutropenic patients, antifungal agents may be used as prophylaxis, as empiric or preemptive therapy, or to treat an invasive fungal disease that has been diagnosed. The hematologist must be familiar with the epidemiology, diagnostic tools and strategies of antifungal use, as well as the pharmacologic proprieties of the different antifungal agents. In this paper the principal antifungal agents used in hematologic patients will be discussed as will the clinical scenarios where these agents have been used.

Keywords : Antifungal agents; Mycoses; Aspergillosis.

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