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Brazilian Archives of Biology and Technology
On-line version ISSN 1678-4324
VEIGA, Marcelo Leite da; RODRIGUES, Edson de Lara; PACHECO, Fabio Juliano and RANZANI-PAIVA, Maria José Tavares. Histopathologic changes in the kidney tissue of Prochilodus lineatus Valenciennes, 1836 (Characiformes, Prochilodontidae) induced by sublethal concentration of Trichlorfon exposure. Braz. arch. biol. technol. [online]. 2002, vol.45, n.2, pp.171-175. ISSN 1678-4324. http://dx.doi.org/10.1590/S1516-89132002000200007.
Studies were carried out to analyse the kidney histopathological alterations of "curimbatá", Prochilodus lineatus, were analyzed. An acute bioassay was made by the water contamination with 0.2mml/l of Dipterex 500 (Trichlorfon). The kidney tissue collected after 24 hours of exposure showed an enlargement of intercapsular space with glomerular atrophy, hypertrophy of the kidney tube cells, with small granules on its cytoplasm and little nuclear alteration. Blood overflowing from capillaries with pyknotic nuclei and vacuoles in the cytoplasm it was also noticed. After 48 hours, the kidney tissue showed glomerular expansion, impossibility to visualize the intercapsular space as well as cytoplasm limit of many cells. The parietal capsular epithelium and the basal membrane presented loss of cell content, the tubular cells appeared swollen vacuolated and with thin and thick cytoplasmatic granulations. Some of the cell nuclei kept relatively regular form with a condensed chromatin on its central region, while others showed themselves relatively small and pyknotics advancing to a cariolisis and necrosis focus.
Keywords : Kidney; Prochilodus lineatus; curimbatá; Trichlorfon.