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Brazilian Archives of Biology and Technology

On-line version ISSN 1678-4324


LOPES, Francisco Luiz Gumes et al. Viability in the production of a drug extracted from Ananas comosus by a flat membrane system. Braz. arch. biol. technol. [online]. 2012, vol.55, n.3, pp.465-470. ISSN 1678-4324.

The aim of this work was to study the production of e bromelain from the Ananas comosus L. Merril, by determining the process conditions using flat membranes. The production system modeling generated a hyperbolical curve and the optimization by response surfaces showed an influence of the transmembrane pressure higher than the pH influence. The cost of the production of bromelain from A. comosus was estimated 9 to 13 times lower than Sigma's retail sales price and 6.5 to 8.5 times lower than when this enzyme was obtained through a liquid-liquid extraction, which showed the economical feasibility of the process.

Keywords : Ananas comosus; bromelain; flat membrane; production cost; optimization.

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