Acessibilidade / Reportar erro

Profile of susceptibility in vitro of Trichosporon asahii and Trichosporon inkin strains against cyclic imides

Perfil de sensibilidade in vitro de cepas de Trichosporon asahii e Trichosporon inkin frente a imidas cíclicas

In vitro susceptibility testing of Trichosporon asahii (13 strains) and T. inkin (13 strains) against cyclic imides (succinimides, naphtalimides and maleimides) in concentrations of 200 to 6,25 µg/mL was performed according to the diffusion agar method. By the results obtained, the antifungal activity of the cyclic imides: 3,4-dichloro-N-phenyl-maleimide; 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-propyl-maleimide (50 µg/mL) over T. asahii and T. inkin was important and it may be helpful in showing perspectives in a search for new antimicotic products.

Antifungals; Trichosporon asahii; Trichosporon inkin; Cyclic imides


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