SciELO - Scientific Electronic Library Online

vol.17 issue4Comparison between two experimental protocols to promote osteoporosis in the maxilla and proximal tibia of female ratsClinical effect of a herbal dentifrice on the control of plaque and gingivitis: a double-blind study author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Pesquisa Odontológica Brasileira

Print version ISSN 1517-7491


PUGLIESE, Lívia Souza; MEDRADO, Alena Peixoto; REIS, Sílvia Regina de Almeida  and  ANDRADE, Zilton de Araújo. The influence of low-level laser therapy on biomodulation of collagen and elastic fibers. Pesqui. Odontol. Bras. [online]. 2003, vol.17, n.4, pp.307-313. ISSN 1517-7491.

The study of low-level laser therapy upon extracellular matrix elements is important to understand the wound healing process under this agent. However, little is known about the interference of laser light in relation to collagen and elastic fibers. Cutaneous wounds were performed on the back of 72 Wistar rats and a Ga-Al-As low-level laser was punctually applied with different energy densities. The animals were killed after 24, 48, 72 hours and 5, 7 and 14 days. Tissues were stained with hematoxilin-eosin, sirius red fast green and orcein and then analyzed. It was observed that the treated group exhibited larger reduction of edema and inflammatory infiltrate. The treated animals presented a larger expression of collagen and elastic fibers, although without statistical significance (p > 0.05). Treatment with a dosage of 4 J/cm² exhibited more expressive results than that with 8 J/cm². In this study, the authors concluded that low-level laser therapy contributed to a larger expression of collagen and elastic fibers during the early phases of the wound healing process.

Keywords : Lasers; Laser therapy; low-level; Wound healing; Collagen.

        · abstract in Portuguese     · text in English     · English ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License