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Brazilian Journal of Microbiology
Print version ISSN 1517-8382
On-line version ISSN 1678-4405
BOAVENTURA, Maria Amélia D.; LOPES, Rosiane F.A.P. and TAKAHASHI, Jacqueline A.. Microorganisms as tools in modern chemistry: the biotransformation of 3-indolylacetonitrile and tryptamine by fungi. Braz. J. Microbiol. [online]. 2004, vol.35, n.4, pp.345-347. ISSN 1517-8382. http://dx.doi.org/10.1590/S1517-83822004000300014.
Chemical reactions performed by microorganisms have been used as a modern tool in chemistry. In this work, the ability of the fungi Beauveria bassiana and Aspergillus niger to modify the chemical structure of indole compounds was studied. Beauveria bassiana was able to transform 3-indolylacetonitrile into 3-methylindole while Aspergillus niger transformed tryptamine into 5-hydroxyindole-3-acetamide. Interestingly, these fungi were able to perform both reduction and oxidation of the indole compounds fed, the oxidation occurring with improved levels of oxygen uptake. The results prove once more the versatility of microorganisms to perform a wide range of industrially attractive chemical reactions.
Keywords : Biotransformations; Beauveria bassiana; Aspergillus niger; 3-indolylacetonitrile; tryptamine.