SciELO - Scientific Electronic Library Online

 
vol.35 issue4Influence of initial L-asparagine and glycerol concentrations on the batch growth kinetics of Mycobacterium bovis BCGHuman respiratory syncytial virus detection in children admitted at a community hospital in Botucatu, SP, Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Brazilian Journal of Microbiology

Print version ISSN 1517-8382

Abstract

BOAVENTURA, Maria Amélia D.; LOPES, Rosiane F.A.P.  and  TAKAHASHI, Jacqueline A.. Microorganisms as tools in modern chemistry: the biotransformation of 3-indolylacetonitrile and tryptamine by fungi. Braz. J. Microbiol. [online]. 2004, vol.35, n.4, pp. 345-347. ISSN 1517-8382.  http://dx.doi.org/10.1590/S1517-83822004000300014.

Chemical reactions performed by microorganisms have been used as a modern tool in chemistry. In this work, the ability of the fungi Beauveria bassiana and Aspergillus niger to modify the chemical structure of indole compounds was studied. Beauveria bassiana was able to transform 3-indolylacetonitrile into 3-methylindole while Aspergillus niger transformed tryptamine into 5-hydroxyindole-3-acetamide. Interestingly, these fungi were able to perform both reduction and oxidation of the indole compounds fed, the oxidation occurring with improved levels of oxygen uptake. The results prove once more the versatility of microorganisms to perform a wide range of industrially attractive chemical reactions.

Keywords : Biotransformations; Beauveria bassiana; Aspergillus niger; 3-indolylacetonitrile; tryptamine.

        · abstract in Portuguese     · text in English     · pdf in English