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Brazilian Journal of Microbiology

versão impressa ISSN 1517-8382versão On-line ISSN 1678-4405

Resumo

GONZALEZ-LOSA, Maria del Refugio et al. Low prevalence of high risk human papillomavirus in normal oral mucosa by hybrid capture 2. Braz. J. Microbiol. [online]. 2008, vol.39, n.1, pp.32-34. ISSN 1517-8382.  http://dx.doi.org/10.1590/S1517-83822008000100008.

High risk human papillomavirus (HR-HPV) are recognized as a necessary factor to development cervical cancer. During the last decade many studies have found HR-HPV in oral squamous cell carcinoma (OSCC) and normal oral mucosa, however the association between HR-HPV and OSCC is still uncertain. The aim of the study was to determine DNA HR-HPV in normal oral cavity of healthy adults. A cross-sectional study was performed; samples from 77 patients with normal oral cavity were collected at the Dentistry school, Autonomous University of Yucatan, Merida, Yucatan, México. HR-HPV was detected by hybrid capture 2. One sample out of 77(1.2%) was positive for HR-PVH. It was from a man of 50 years old. HR-HPV is present in low rate among healthy oral mucosa. Hybrid capture 2 could be a good methodology for large epidemiology studies.

Palavras-chave : Papillomavirus; hybrid capture 2; oral mucosa; squamous cell carcinoma; high risk.

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