Brazilian Journal of Microbiology
On-line version ISSN 1678-4405
SEVERINO, Vanessa Gisele Pasqualotto et al. Determination of the antibacterial activity of crude extracts and compounds isolated from Hortia oreadica (Rutaceae) against oral pathogens. Braz. J. Microbiol. [online]. 2009, vol.40, n.3, pp. 535-540. ISSN 1678-4405. http://dx.doi.org/10.1590/S1517-83822009000300015.
Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms.
Keywords : Hortia oreadica; Rutaceae; antibacterial activity; MIC; oral pathogens.