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Revista Brasileira de Medicina do Esporte

Print version ISSN 1517-8692On-line version ISSN 1806-9940


SALES, Ricardo Pombo et al. Effects of the acute arginine aspartate supplement on the muscular fatigue in trained volunteers. Rev Bras Med Esporte [online]. 2005, vol.11, n.6, pp.347-351. ISSN 1517-8692.

The physical activity influences specific mechanisms responsible by a reduction in the power production, and consequently on the fatigue. It has been proposed premises to improve the physical performance, and we observed that some studies have been focused on the reduction of the metabolites that decrease the fatigue on intense physical exercising, using aminoacids known for their properties to induce to metabolic changes, and among these, it is the arginine. The present study had the purpose to study the effects of the acute arginine aspartate supplement in trained healthy individuals submitted to an exhaustion protocol on ergonomic bicycle. Twelve 22.6 ± 3.5 years old trained individuals were used in the research. After taking a single dose of arginine aspartate or a placebo solution, they performed three 90 minute test on an ergonomic bicycle to which load increments were added up to reaching the exhaustion. The blood samples were obtained through biochemical analysis, such as: creatinine, urea, glycosis, and lactate. It was found no statistical differences upon the comparison of the Maximal Heart Rate, Maximal Time and Load, and also comparing to the previous and later results on the urea, creatinine and glycosis tests. The lactate concentrations (mmol/l) presented statistical differences compared to the pre-test values (Control: 2.2 ± 0.14; Arginine: 2.43 ± 0.23; Placebo: 2.26 ± 0.11) to the post-test values (Control 10.35 ± 0.57; Arginine: 12.07 ± 0.88; Placebo: 12.2 ± 0.96), p < 0.001. The main results found in this study indicate that the acute administration of the arginine aspartate did not show effective to increase the fatigue tolerance in the individuals evaluated and treated in the incremental test protocol up to the exhaustion. Thus, it can be concluded that the dosage used was not able to increase the muscular fatigue tolerance.

Keywords : Lactate; Aminoacid; Exhaustion.

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