SciELO - Scientific Electronic Library Online

vol.13 issue3Comparison of absolute and relative phisiological responses of cyclists and triathletes author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista Brasileira de Medicina do Esporte

Print version ISSN 1517-8692On-line version ISSN 1806-9940


DIAS, Rodrigo Gonçalves; PEREIRA, Alexandre da Costa; NEGRAO, Carlos Eduardo  and  KRIEGER, José Eduardo. Genetic polymorphisms determining of the physical performance in elite athletes. Rev Bras Med Esporte [online]. 2007, vol.13, n.3, pp.209-216. ISSN 1517-8692.

This article is focused on the review of studies looking for "candidate genes" and their relationship with physical performance phenotypes in elite athletes. Our goal is to bring to readers what makes some individuals excel in some sports modalities, based on variants in genetic loci and markers. In addition, we assume the necessity to describe by what mechanisms a gene can contribute in physical performance, detailing in each part the cellular, physiological and molecular pathways involved. For this reason, we limited our discussion to a small number of genetic variants: polymorphisms R577X a-actinin 3 gene (ACTN3), C34T AMP deaminase gene (AMPD1), I/D angiotensin converting enzyme gene (ACE), -9/+9 b2 bradykinin receptor gene (BDKRB2), and 985+185/ 1170 creatine kinase M gene (CK-M). We hope that this article bring some new information and refine the knowledge to the fact that the process of talent identification and an individual athletic potential maximization resulting in sport success are strongly associated with genetic variants.

Keywords : Gene; Genetic polimorphism; Human physical performance.

        · abstract in Portuguese     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License