Services on Demand
Revista Brasileira de Medicina do Esporte
On-line version ISSN 1806-9940
CRUZAT, Vinicius Fernandes; ROGERO, Marcelo Macedo; BORGES, Maria Carolina and TIRAPEGUI, Julio. Current aspects about oxidative stress, physical exercise and supplementation. Rev Bras Med Esporte [online]. 2007, vol.13, n.5, pp. 336-342. ISSN 1806-9940. http://dx.doi.org/10.1590/S1517-86922007000500011.
Oxygen reactive species (ORE) are usually produced by the body metabolism. However, ORE present the ability to remove electrons from other cellular composites, being able to cause oxidative injuries in several molecules. Such fact leads to a total loss of cellular function. Physical exercise practice increases ORE synthesis, besides promoting muscular injury and inflammation. After a physical exercise set, the recovery phase begins, where several effects positive to health are observed, including increase in resistance to new injuries induced or not by exercise, a fact which is considered an 'adaptation' process. Many studies though, have reported that this recovery is not reached by individuals who are submitted to intense and extended exercises, or even, who have high training frequency. Nutritional alternatives have been widely studied, in order to reduce the effects promoted by extenuating exercise, among which vitamin E, vitamin C, creatine and glutamine supplementation is included. This review has the aim to approach the current aspects concerning the ORE formation, the cellular injury and inflammation processes, the adaptation to the kinds of aerobic and anaerobic exercise, besides possible nutritional interventions.
Keywords : Oxygen reactive species; Adaptation; Vitamins; Creatine; Glutamine.