Relationship of databases of live births and infant deaths for analysis of congenital malformations

Guimarães, Aline Luzia Sampaio; Barbosa, Celivane Cavalcanti; Oliveira, Conceição Maria de; Maia, Lívia Teixeira de Souza; Bonfim, Cristine Vieira do

doi:10.1590/1806-93042019000400010

Acessibilidade / Reportar erro

Brasil

Revista Brasileira de Saúde Materno Infantil

Español English

Brasil

Español English

sumário « anterior atual seguinte »

Sumário

ORIGINAL ARTICLES • Rev. Bras. Saude Mater. Infant. 19 (4) • Oct-Dec 2019 • https://doi.org/10.1590/1806-93042019000400010 copy

Relationship of databases of live births and infant deaths for analysis of congenital malformations

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

Objectives:

to describe the prevalence of congenital malformations in live births in Recife, based on the relationship of birth and infant death data.

Methods:

a cross-sectional study with data from the Live Birth Information System (Sinasc) and Mortality (MIS) of residents in Recife-PE between 2013 and 2015. The deterministic linkage of deaths and live births (LB) with malformation and the prevalence rate were calculated.

Results:

545 (95.1%) deaths and live births were matched. According to the Sinasc, the prevalence of congenital malformations was 10.4 per 1,000 LB. After the linkage, the rate was 12.4. Malformations of the musculoskeletal system (42.1%) among live births were high-lighted, as well as malformations of the circulatory system (35.3%) found in infant deaths.

Conclusions:

linkage increased the prevalence of congenital malformations in the studied cohort. This demonstrates the potential of this strategy for the monitoring of congenital malformations, which can be used to monitor infant death.

Key words:
Congenital abnormalities; Vital statistics; Infant mortality; Information systems

Congenital malformations	Live births
Congenital malformations	n	%	Prevalence
Of the nervous system
(Q00 - Q07)	33	6.8	0.7
Eye, ear, face, neck
(Q10 - Q18)	31	6.4	0.7
Of the circulatory system
(Q20 - Q28)	29	6.0	0.6
Of the respiratory system
(Q30 - Q34)	9	1.9	0.2
Cleft lip and cleft palate
(Q35 - Q37)	20	4.1	0.4
Other congenital malformations of the digestive tract
(Q38 - Q45)	17	3.5	0.4
Of genital organs
(Q50 - Q56)	56	11.6	1.2
Of the urinary tract
(Q60 - Q64)	7	1.4	0.1
Congenital malformations and deformities of musculoskeletal system
(Q65-Q79)	204	42.1	4.4
Other congenital malformations
(Q80 - Q89)	18	3.7	0.4
Chromosomal anomalies, not elsewhere classified
(Q90 - Q99)	21	4.3	0.4
Multiple malformations	40	8.2	0.9
Total 485	100.0	10.4

Source	Pre-linkage			Post-linkage			Increment
Source	n	%	Prevalence	n	%	Prevalence	n	%
MIS	180	33.0	3.8	184	33.7	3.9	4	2.2
Sinasc	485	1.0	10.4	582	1.2	12.4	97	20.0

Congenital malformations	Deaths
Congenital malformations	n	%	Prevalence
Of the nervous system
(Q00 - Q07)	19	10.3	0.4
Eye, ear, face, neck
(Q10 - Q18)	2	1.1	-
Of the circulatory system
(Q20 - Q28)	65	35.3	1.4
Of the respiratory tract
(Q30 - Q34)	9	4.9	0.2
Cleft lip and cleft palate
(Q35 - Q37)	1	0.5	-
Of the digestive system
(Q38 - Q45)	9	4.9	0.2
Of the genital organs
(Q50 - Q56)	1	0.5	-
Of the urinary tract
(Q60 - Q64)	5	2.7	0.1
Of the musculoskeletal system
(Q65-Q79)	23	12.5	0.5
Other congenital malformations
(Q80 - Q89)	22	12.1	0.5
Chromosomal anomalies, not elsewhere classified
(Q90 - Q99)	28	15.2	0.6
Total 184	100.0	3.9

Congenital malformations	Live births
	Pre-linkage				Post-linkage		Increment
	n	%	Prevalence	n	%	Prevalence	n	%
Of the nervous system
(Q00 - Q07)	33	6.8	0.7	40	6.9	0.8	7	21.2
Eye, ear, face, neck
(Q10 - Q18)	31	6.4	0.7	31	5.3	0.7	-	-
Of the circulatory system
(Q20 - Q28)	29	6.0	0.6	78	13.4	1.7	49	169.0
Of the respiratory tract
(Q30 - Q34)	9	1.9	0.2	9	1.5	0.2	-	-
Cleft lip and cleft palate
(Q35 - Q37)	20	4.1	0.4	20	3.4	0.4	-	-
Of the digestive system
(Q38 - Q45)	17	3.5	0.4	23	4.0	0.5	6	35.2
Of the genital organs
(Q50 - Q56)	56	11.6	1.2	56	9.6	1.2	-	-
Of the urinary tract
(Q60 - Q64)	7	1.4	0.1	10	1.7	0.2	3	42.8
Of the musculoskeletal system
(Q65-Q79)	204	42.1	4.4	213	36.6	4.5	9	4.4
Other malformations (Q80 - Q89)	18	3.7	0.4	26	4.5	0.5	8	44.4
Chromosomal anomalies, not
elsewhere classified (Q90 - Q99)	21	4.3	0.4	36	6.2	0.8	15	71.4
Multiple malformations	40	8.2	0.9	40	6.9	0.9	-	-
Total	485	100.0	10.4	582	100.0	12.4	97	20.0

Instituto de Medicina Integral Prof. Fernando Figueira Rua dos Coelhos, 300. Boa Vista, 50070-550 Recife PE Brasil, Tel./Fax: +55 81 2122-4141 - Recife - PR - Brazil
E-mail: revista@imip.org.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Author’s contribution

All authors participated in the study design, data analysis, interpretation of results, text writing, writing and approval of the final version of the manuscript, and are responsible for all aspects of the research, including ensuring its accuracy and completeness.