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vol.14 número1Gestão de Qualidade Empresarial: how this teory can useful in research of fenomeno of death is sudden unexpected death in epilepsy?West Syndrome, autism and epilepsy: resolution of the epilepsy and recover of autism after surgery índice de autoresíndice de materiabúsqueda de artículos
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Journal of Epilepsy and Clinical Neurophysiology

versión impresa ISSN 1676-2649versión On-line ISSN 1980-5365


GOMES, Maria Durce Costa; GARZON, Eliana  y  SAKAMOTO, Américo C.. The 50 years experience of adrenocorticotropic hormone (ACTH) use in West Syndrome: literatura review and UNIFESP protocol. J. epilepsy clin. neurophysiol. [online]. 2008, vol.14, n.1, pp.27-32. ISSN 1676-2649.

INTRODUCTION: It is extensively discussed in the literature the efficacy of ACTH in West Syndrome (WS) as well, dosage, best protocols and side effects. OBJECTIVE: Analyze and discuss the most recent and relevant publication related to ACTH in patients with WS. METHODOLOGY: Literature publication was selected from MEDLINE and PUBMED between 1997 to 2007 using the following key words: "ACTH" and " West Syndrome". RESULTS: 96 titles were referral at medline and 158 at pubmed. 22 were selected and previous studies with special relevance were also included. CONCLUSIONS: There are evidences that ACTH probably has efficacy for immediately control of spasms and hypsarrhythmia. There is no evidence about the efficacy of ACTH in long term concerning seizures control and prevent delayed developmental).

Palabras clave : ACTH; West Syndrome; infantile spasms; hypsarrhythmia.

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