Journal of Epilepsy and Clinical Neurophysiology
versión impresa ISSN 1676-2649
ARAUJO FILHO, Gerardo Maria de; MAZETTO, Lenon y YACUBIAN, Elza Márcia Targas. Psychiatric and behavioral effects of the antiepileptic drugs and their action as mood stabilizers. J. epilepsy clin. neurophysiol. [online]. 2011, vol.17, n.2, pp. 65-69. ISSN 1676-2649. http://dx.doi.org/10.1590/S1676-26492011000200006.
INTRODUCTION: The association between epilepsy, psychiatric disorders (PD) and antiepileptic drugs (AED) is among the most frequent and important aspects of epileptology. According to most recent data in literature, AED can act as protecting or predisposing to psychiatric disorders. OBJECTIVE: Data regarding the psychiatric and behavioral effects of AED and its action as mood stabilizers were reviewed. In addition, we discuss the relationship between AED effects in predisposing or protect against PD and its respective mechanism of action. CONCLUSION: AED do not have only antiepileptic properties, but may be associated to positive or negative behaviors. However, the appearance of PD is associated to both AED mechanism of action and the patient's individual predisposing.
Palabras llave : psychiatric disorders; epilepsy; antiepileptic drugs.