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Jornal Vascular Brasileiro
On-line version ISSN 1677-7301
SAPIENZA, Marcelo Tatit et al. Criteria for semi-quantitative analysis of lymphoscintigraphy in lower limb lymphedema. J. vasc. bras. [online]. 2006, vol.5, n.4, pp. 288-294. ISSN 1677-7301. http://dx.doi.org/10.1590/S1677-54492006000400008.
OBJECTIVE: To evaluate whether different parameters could be used in the analysis of lymphoscintigraphy to distinguish affected from unaffected limbs in patients with unilateral edema. METHODS: Twenty patients who underwent lymphoscintigraphy for screening of unilateral lower limb edema were retrospectively assessed and divided into patients with primary lymphedema (group 1, n = 7) or secondary post-traumatic edema (group 2, n = 13). Technetium 99m-labeled human serum albumin was subdermally administered in the feet, followed by a dynamic lymphoscintigraphy of the pelvis during 15 min and static images of the lower limbs after 15 min and 1 h. Analyzed parameters were detection time of groin activity, semi-quantitative index (lymph flow, interstitial diffusion, aspect of vessels, detection time and aspect of inguinal lymph nodes) and slope of groin time-activity curve. The parameters of clinically affected limbs were compared to those of the contralateral limbs in both groups. RESULTS: Detection time of groin activity and semi-quantitative index were significantly higher in affected limbs considering all patients, with a more severe delay and a higher semi-quantitative index in group 1 compared to group 2. CONCLUSION: Analysis of detection time of groin activity and semi-quantitative index can add objective parameters that can be used in the diagnosis and follow-up of patients with lymphedema.
Keywords : Scintigraphy; lymphedema.