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The influence of diabetes mellitus on patency of arteriovenous fistulas for hemodialysis

Abstract

Background

Failure of arteriovenous fistulas (AVFs) to meet the minimum requirements for hemodialysis (HD) is the greatest cause of morbidity in patients on renal replacement therapy. Identifying risk factors associated with failure of vascular access is crucial to management and success of hemodialysis treatment.

Objective

To compare mean duration of patency and survival of arteriovenous fistulas created in HD patients with and without diabetes mellitus (DM).

Methods

This was a retrospective observational study of the medical records for all patients on HD at the Hospital Santa Casa de Misericórdia de Ponta Grossa (Brazil) in February 2014. We analyzed clinical data relating to creation, maintenance and use of AVF for dialysis, comparing mean duration of patency of fistulas currently in use for HD and analyzing survival of previously occluded AVFs. Patient data was allocated to one of two groups for analysis, according to presence or absence of DM.

Results

Individuals in the DM group had higher mean age (59.97 ± 10.12), shorter time on hemodialysis treatment (25.42 ± 3.21 months), lower mean time before occlusion of arteriovenous fistulas (3.09 ± 11.60 months) and a lower mean rate survival of vascular access to 24 months (50.25%).

Conclusions

This study concluded that diabetic patients had shorter mean duration of AVF patency and lower rate of access survival to 24 months.

Keywords:
renal dialysis; arteriovenous fistula; diabetes mellitus

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