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Jornal Vascular Brasileiro

Print version ISSN 1677-5449On-line version ISSN 1677-7301

Abstract

BARBALHO, Sandra Maria et al. Metabolic syndrome, atherosclerosis and inflammation: an inseparable triad?. J. vasc. bras. [online]. 2015, vol.14, n.4, pp.319-327.  Epub Dec 01, 2015. ISSN 1677-5449.  http://dx.doi.org/10.1590/1677-5449.04315.

Populations all over the world are increasingly inactive and are consuming increasing quantities of fats and sugars, which is generally linked to industrially processed foods. The consequences have rapidly manifest as an increase in overweight/obesity and in physiological and metabolic changes, such as the Metabolic Syndrome, which is a series of changes in glycemia, lipids and blood pressure. There is evidence of a close relationship between these changes and inflammatory processes, which can also be linked to oxidative stress. These conditions lead to the pathogenesis of vascular abnormalities or intensify metabolic processes that accompany the metabolic syndrome. The objective of this review is to compare the large number of bibliographic references that show correlations between components of the Metabolic Syndrome and increases in the mediators of inflammation. The publications reviewed were located using the Pubmed, Scopus, Lilacs and Scielo databases and the majority of the articles selected were published within the last 5 years.

Keywords : metabolic syndrome; arteriosclerosis; inflammation.

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