Jiménez-Gómez et al.77 Jiménez-Gómez Y, Marín C, Peérez-Martínez P, et al. A low-fat, high-complex carbohydrate diet supplemented with long-chain (n-3) fatty acids alters the postprandial lipoprotein profile in patients with metabolic syndrome. J Nutr. 2010;140(9):1595-601. http://dx.doi.org/10.3945/jn.109.120816. PMid:20631323. http://dx.doi.org/10.3945/jn.109.120816...
|
Randomized |
130 people with MS BMI = NR Age = NR |
8 hours |
Group 1: 38% SFA Group 2: 43% MUFA Group 3: low fat diet (28%) + omega 3 Group 4: low fat diet (28%) |
43% of total lipids |
accentuated ↑ in TAG, returning to baseline in a shorter time than other groups |
Hartwich et al.88 Hartwich J, Leszczynska-Golabek I, Kiec-Wilk B, et al. Lipoprotein profile, plasma ischemia modified albumin and LDL density change in the course of postprandial lipemia. Insights from the LIPGENE study. Scand J Clin Lab Invest. 2010;70(3):201-8. http://dx.doi.org/10.3109/00365511003663630. PMid:20233037. http://dx.doi.org/10.3109/00365511003663...
|
Randomized |
164 people with MS criteria BMI = 20 to 40 kg/m2 Age = 35 to 70 years |
8 hours |
Group1: 16% SFA Group2: 20% MUFA Group 3: low fat diet + omega 3 Group 4: low fat diet |
20% of TCV of the meal |
accentuated ↑ in TAG, returning to baseline in a shorter time than other groups |
Bouwens et al.99 Bouwens M, Grootte Bromhaar M, Jansen J, Müller M, Afman LA. Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles. Am J Clin Nutr. 2010;91(1):208-17. http://dx.doi.org/10.3945/ajcn.2009.28586. PMid:19923369. http://dx.doi.org/10.3945/ajcn.2009.2858...
|
Randomized Single-blind Crossover |
21 healthy men BMI = 18 to 27 kg/m2 Age 19 to 27 years |
6 hours |
Group1: 70% SFA Group 2: 80% MUFA Group 3: 65% PUFA |
55 g (80% of total lipids) |
Greater reduction in cholesterol after 6h compared to other groups |
Perez-Martinez et al.11 Perez-Martinez P, Ordovas JM, Garcia-Rios A, et al. Consumption of diets with different type of fat influences triacylglycerols-rich lipoproteins particle number and size during the postprandial state. Nutr Metab Cardiovasc Dis. 2011;21(1):39-45. http://dx.doi.org/10.1016/j.numecd.2009.07.008. PMid:19819118. http://dx.doi.org/10.1016/j.numecd.2009....
|
Randomized Crossover |
20 healthy men BMI = 24.5±2.7 kg/m2 Age = 22±1.8 years |
11 hours |
Group 1: 35% SFA Group 2: 36% MUFA Group 3: 55% CHO+ 8% PUFA |
36% of total lipids |
↓ in total number and ↑ in size of TRL ↓ cardiovascular risk compared to other groups |
Lopez et al.1010 Lopez S, Bermudez B, Ortega A, et al. Effects of meals rich in either monounsaturated or saturated fat on lipid concentrations and on insulin secretion and action in subjects with high fasting triglyceride concentrations. Am J Clin Nutr. 2011;93(3):494-9. http://dx.doi.org/10.3945/ajcn.110.003251. PMid:21209225. http://dx.doi.org/10.3945/ajcn.110.00325...
|
Crossover |
14 hypertriglyceridemic men BMI = 24.2±5.1 kg/m2 Age = 33±7 years |
8 hours |
Group1: 10 kcal of MUFA per kg of body weight Group2: 10 kcal of SFA per kg of body weight Group 3: Control (without lipids) |
10 kcal/kg weight |
↑ TAG, ↑ NEFA, ↑ insulin (Groups 1 and 2) |
Teng et al.1111 Teng KT, Nagapan G, Cheng HM, Nesaretnam K. Palm olein and olive oil cause a higher increase in postprandial lipemia compared with lard but had no effect on plasma glucose, insulin and adipocytokines. Lipids. 2011;46(4):381-8. http://dx.doi.org/10.1007/s11745-010-3516-y. PMid:21197586. http://dx.doi.org/10.1007/s11745-010-351...
|
Randomized Single-blind Crossover |
10 healthy men BMI = 21±1.6 kg/m2 Age = 21.9±0.7 years |
4 hours |
Group 1: 50 g of MUFA Group 2: 50 g of SFA Group 3: 50 g of PUFA |
50 g |
↑ in TAG was greatest in Group 1, followed by Group 2 |
Lozano et al.1212 Lozano A, Perez-Martinez P, Delgado-Lista J, et al. Body mass interacts with fat quality to determine the postprandial lipoprotein response in healthy young adults. Nutr Metab Cardiovasc Dis. 2012;22(4):355-61. http://dx.doi.org/10.1016/j.numecd.2010.07.013. PMid:21093231. http://dx.doi.org/10.1016/j.numecd.2010....
|
Randomized Crossover |
21 healthy men BMI > 26.18 kg/m2 and BMI < 26.18 kg/m2 Age = 23±1.5 years |
11 hours |
Group 1: 38% MUFA Group 2: 35% SFA Group 3: 20% SFA, 24% MUFA and 16% PUFA |
38% of TCV of the meal |
↓ TRL-TAG compared to other groups |
Van Dijk et al.1313 Van Dijk S, Feskens E, Bos MB, et al. Consumption of a high monounsaturated fat diet reduces oxidative phosphorylation gene expression in peripheral blood mononuclear cells of abdominally overweight. J Nutr. 2012;142(7):1219-25. http://dx.doi.org/10.3945/jn.111.155283. PMid:22623392. http://dx.doi.org/10.3945/jn.111.155283...
|
Randomized Crossover |
42 men (healthy weight, obese and obese with type 2 diabetes) BMI = NR Age = 50 to 70 years |
4 hours |
Group 1: 51 g of SFA Group 2: 79 g of MUFA Group 3: 38 g of PUFA |
79 g |
↓ Free fatty acids over time (MUFA > SFA > PUFA) |
Lozano et al.22 Lozano A, Perez-Martinez P, Marin C, et al. An acute intake of a walnut-enriched meal improves postprandial adiponectin response in healthy young adults. Nutr Res. 2013;33(12):1012-8. http://dx.doi.org/10.1016/j.nutres.2013.08.010. PMid:24267040. http://dx.doi.org/10.1016/j.nutres.2013....
|
Randomized Crossover |
21 men BMI = NR Age = 23±1.5 years |
11 hours |
Group 1: 38% MUFA Group 2: 35% SFA Group 3: 20% SFA, 24% MUFA and 16% PUFA |
38% of TCV of the meal |
No differences between groups |
Raz et al.1414 Raz O, Steinvil A, Berliner S, Rosenzweig T, Justo D, Shapira I. The effect of two iso-caloric meals containing equal amounts of fats with a different fat composition on the inflammatory and metabolic markers in apparently healthy volunteers. J Inflamm. 2013;10(1):3. http://dx.doi.org/10.1186/1476-9255-10-3. PMid:23369030. http://dx.doi.org/10.1186/1476-9255-10-3...
|
Crossover |
54 individuals BMI = 25±0.9 kg/m2 Age = 41.7±3.1 years |
4 hours |
Group 1: 51 g of MUFA Group 2: 51 g of SFA |
51 g |
↑ in TAG smaller after MUFA |
Pietraszek et al.1515 Pietraszek A, Gregersen S, Pedersen SB, Holst JJ, Hermansen K. Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes. Eur J Clin Nutr. 2014;68(9):1022-8. http://dx.doi.org/10.1038/ejcn.2014.64. PMid:24824014. http://dx.doi.org/10.1038/ejcn.2014.64...
|
NR |
17 healthy people 17 people with DM2 BMI= NR Age = NR |
4 hours |
Group 1: free from DM2, MUFA intake Group 2: with DM2, MUFA intake |
67 g |
Healthy people responded better to treatment |
Cabello-Moruno et al.1616 Cabello-Moruno R, Martinez-Force E, Montero E, Perona JS. Minor components of olive oil facilitate the triglyceride clearance from postprandial lipoproteins in a polarity-dependent manner in healthy men. Nutr Res. 2014;34(1):40-7. http://dx.doi.org/10.1016/j.nutres.2013.10.003. PMid:24418245. http://dx.doi.org/10.1016/j.nutres.2013....
|
Randomized Crossover |
10 healthy men BMI = 23.7±2 kg/m2 Age = 26±4.3 years |
6 hours |
Group 1: 70 g pomace olive oil (MUFA) Group 2: 70 g refined olive oil (MUFA) |
70 g |
No differences in TAG between groups Larger TRL Particles in the pomace group |