Journal of Applied Oral Science
versão On-line ISSN 1678-7765
ESTRELA, Carlos; SYDNEY, Gilson Blitzkow; FIGUEIREDO, José Antonio Poli e ESTRELA, Cyntia Rodrigues de Araújo. Antibacterial efficacy of intracanal medicaments on bacterial biofilm: a critical review. J. Appl. Oral Sci. [online]. 2009, vol.17, n.1, pp. 1-7. ISSN 1678-7765. http://dx.doi.org/10.1590/S1678-77572009000100002.
The purpose of this paper is to discuss critically the antibacterial efficacy of intracanal medicaments on bacterial biofilm. Longitudinal studies were evaluated by a systematic review of English-language articles retrieved from electronic biomedical journal databases (MEDLINE, EMBASE, CENTRAL) and handsearching records, using different matches of keywords for root canal biofilm, between 1966 and August 1st, 2007. The selected articles were identified from titles, abstracts and full-text articles by two independent reviewers, considering the tabulated inclusion and exclusion criteria. Disagreements were resolved by consensus. The search retrieved 91 related articles, of which 8.8% referred to in vivo studies demonstrating the lack of efficacy of endodontic therapy on bacterial biofilm. Intracanal medicaments were found to have a limited action against bacterial biofilm.
Palavras-chave : Biofilm; Intracanal medicaments; Antimicrobial efficacy.