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Journal of Venomous Animals and Toxins including Tropical Diseases

On-line version ISSN 1678-9199

Abstract

DIAS-BAPTISTA, I. M. F.; USO, S. M. R. S.  and  MARCONDES-MACHADO, J.. Trends in multidrug-resistant tuberculosis. J. Venom. Anim. Toxins incl. Trop. Dis [online]. 2008, vol.14, n.2, pp.203-223.  Epub Oct 22, 2007 ISSN 1678-9199.  http://dx.doi.org/10.1590/S1678-91992007007500001.

Multidrug-resistant tuberculosis (MDR-TB) is an increasing global problem. The extent and burden of MDR-TB varies significantly from country to country and region to region. Globally, about three per cent of all newly diagnosed patients have MDR-TB and the proportion is higher in patients who had previously received anti-tuberculosis (anti-TB) treatment reflecting the failure of programs designed to ensure complete cure of patients with tuberculosis. The management of MDR-TB is a challenge that should be undertaken by experienced clinicians at centers equipped with reliable laboratory services and implementation of DOTS-Plus strategy.

Keywords : Tuberculosis; MDR-TB; XDR-TB; DOTS; DOTS-Plus.

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