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Journal of Venomous Animals and Toxins including Tropical Diseases

On-line version ISSN 1678-9199

Abstract

GERAIX, J.; CARVALHAES, M. A. B. L.  and  PEREIRA, P. C. M.. Different nutritional-state indicators of HIV-positive individuals undergoing antiretroviral therapy. J. Venom. Anim. Toxins incl. Trop. Dis [online]. 2008, vol.14, n.2, pp.338-356. ISSN 1678-9199.  http://dx.doi.org/10.1590/S1678-91992008000200011.

This study aimed at learning about the nutritional profile of HIV-positive individuals undergoing antiretroviral therapy and at comparing the performance of nutritional-state indicators. A transversal study was performed on 94 patients attending the Tropical Diseases Outpatient Hospital of Botucatu Medical School (FMB) - UNESP. The body mass index (BMI) and the classification by Papini-Berto (PB) were used to evaluate nutritional state, aiming at detecting malnutrition and obesity. The waist-to-hips ratio (W/HR) and waist circumference (WC) were adopted for identification of abdominal obesity and lipodystrophy. According to BMI, most of the individuals were eutrophic, followed by 30.9% overweight and 6.4% malnourished. By using the PB classification, the frequency of malnourished increased (22.3%). The analysis of the PB classification in relation to BMI indicated that the former presented high sensitivity and good specificity for malnutrition diagnosis, namely 100% and 83%, respectively. The prevalence of abdominal obesity was 7.44% according to WC, and a higher prevalence (38.3%) was observed when taking W/HR into account. There was significant positive association between nutritional diagnosis according to PB and T CD4+ lymphocyte. The results support the use of PB classification for malnutrition detection as well as that of BMI and W/HR for overweight and fat redistribution.

Keywords : HIV; AIDS; antiretroviral therapy; nutritional indicators.

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