SciELO - Scientific Electronic Library Online

 
vol.10 issue2Spectral characteristics of the hippocampal LFP during contextual fear conditioningSeeking tools for image fusion between computed tomography, structural and functional magnetic resonance methods for applications in neurosurgery author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Einstein (São Paulo)

Print version ISSN 1679-4508

Abstract

CAOUS, Cristofer André; SMITH, Ricardo Luís; HAAPALAINEN, Edna Freymuller  and  LINDSEY, Charles Julian. Ultrastructural transneuronal degeneration study of axonal elements within the paratrigeminal nucleus in sinoaortic deafferented rats. Einstein (São Paulo) [online]. 2012, vol.10, n.2, pp. 145-150. ISSN 1679-4508.  http://dx.doi.org/10.1590/S1679-45082012000200006.

OBJECTIVE: Morphological study that searched to authenticate the presence of sinoaortic baroreceptor inputs within the dorsolateral medullary nucleus under electron microscopy analysis. METHODS: After a 5-day survival period, 9 baroreceptor-denervated rats deeply anaesthetized with equithesin were transcardially perfused and their brains were histologically processed. RESULTS: The neuronal cytoarchitecture of the paratrigeminal nucleus comprehends afferent projections from other nuclei that have a distributive character regarding visceral and nociceptive functions in the cardiovascular reflex integration response. CONCLUSION: The medial portion of the nucleus receives afferent projections of the rostral ventrolateral medulla, as shown by retrograde neurotracing studies. The present results show that the medial extent of the paratrigeminal nucleus contains degenerated axoplasmic cellular components in sinoaortic deafferented rats. The number of degenerated axonal fibers was also larger in this area of the nucleus.

Keywords : Nerve degeneration; Trigeminal nucleus, spinal; Baroreflex; Denervation; Microscopy, electron; Medulla oblongata.

        · abstract in Portuguese     · text in English | Portuguese     · pdf in English | Portuguese