SciELO - Scientific Electronic Library Online

vol.10 issue3Pandemic influenza A/H1N1: comparative analysis of microscopic lung histopathological findingsDementia Rating Scale psychometric study and its applicability in long term care institutions in Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Einstein (São Paulo)

Print version ISSN 1679-4508


GUENDLER, Vera Zukerman et al. Factors associated with acute medication overuse in chronic migraine patients. Einstein (São Paulo) [online]. 2012, vol.10, n.3, pp.312-317. ISSN 1679-4508.

OBJECTIVE: To evaluate the prevalence of psychiatric disorders in patients diagnosed with chronic migraine with and without acute medication overuse. METHODS: Seventy-two volunteers were recruited from a Family Health Program of the Paraisópolis community in São Paulo (SP), Brazil. These patients were submitted to a detailed headache questionnaire. All participants were submitted to physical and neurological examinations. The following variables were analyzed: age, gender, education level, body mass index, type of overused medication, headache characteristics, and caffeine consumption, lifetime anxiety and mood disorders. RESULTS: Out of 72 patients, 50 (69%) had chronic migraine with medication overuse, and 22 (31%) had chronic migraine without medication overuse. Factors such as age, gender, education level, body mass index, type of overused medication, headache characteristics, and caffeine consumption were not significantly different between the two studied groups. Lifetime anxiety and mood disorders were more common in patients with acute medication overuse (p=0.003 and p=0.045, respectively). CONCLUSION: This study has shown a significant association among chronic migraine and medication overuse with lifetime mood and anxiety disorders in patients of the studied population. No association was found for other researched psychiatric disorders.

Keywords : Migraine disorders [drug therapy]; Chronic disease; Mental disorders; Prevalence; Comorbidity.

        · abstract in Portuguese     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License