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Einstein (São Paulo)

Print version ISSN 1679-4508On-line version ISSN 2317-6385

Abstract

PEREIRA, José Leonardo Faustini et al. Ventilatory support and hospital stay after liver transplant in cirrhotic patients with hepatopulmonary syndrome. Einstein (São Paulo) [online]. 2017, vol.15, n.3, pp.322-326. ISSN 2317-6385.  http://dx.doi.org/10.1590/s1679-45082017ao4081.

Objective

To compare mechanical ventilation time, need for non-invasive ventilation, length of intensive care unit stay, and hospital stay after liver transplant in cirrhotic patients with and with no diagnosis of hepatopulmonary syndrome.

Methods

This was a prospective cohort study with a convenience sample of 178 patients (92 with hepatopulmonary syndrome) who were diagnosed as alcoholic or hepatitis C virus cirrhosis. The statistical analysis included Kolmogorov-Smirnov test and Students t test. Data were analyzed using SPSS version 16.0, and p values <0.05 were considered significant.

Results

Out of 178 patients, 90 underwent transplant (48 with no hepatopulmonary syndrome). The Group diagnosed with Hepatopulmonary Syndrome had longer mechanical ventilation time (19.5±4.3 hours versus 12.5±3.3 hours; p=0.02), an increased need for non-invasive ventilation (12 versus 2; p=0.01), longer intensive care unit stay (6.7±2.1 days versus 4.6±1.5 days; p=0.02) and longer hospital stay (24.1±4.3 days versus 20.2±3.9 days; p=0.01).

Conclusion

Cirrhotic patients Group diagnosed with Hepatopulmonary Syndrome had higher mechanical ventilation time, more need of non-invasive ventilation, as well as longer intensive care unit and hospital stay.

Keywords : Liver cirrhosis/etiology; Hepatopulmonary syndrome/complications; Respiration, artificial; Length of stay; Noninvasive ventilation; Intensive care units.

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